(Q22007981)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

The lipid phosphatase activity of PTEN is critical for its tumor supressor function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity

6 December 2019

main subject

2 references

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0051800

Phosphatase and tensin homolog

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

7

M H Wigler

M H

Wigler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

M P Myers

1

M P

Myers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

I Pass

2

I

Pass

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

I H Batty

3

I H

Batty

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

J Van der Kaay

4

J

Van der Kaay

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

J P Stolarov

5

J P

Stolarov

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

B A Hemmings

6

B A

Hemmings

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

C P Downes

8

C P

Downes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

N K Tonks

9

N K

Tonks

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

language of work or name

English

0 references

publication date

1 November 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

6 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

volume

95

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

page(s)

13513-13518

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

6 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Pten is essential for embryonic development and tumour suppression

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Signalling through the lipid products of phosphoinositide-3-OH kinase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Role of translocation in the activation and function of protein kinase B

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Cowden syndrome and Lhermitte-Duclos disease in a family: a single genetic syndrome with pleiotropy?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

A target for phosphoinositide 3-kinase: Akt/PKB.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

PTEN: sometimes taking it off can be better than putting it on.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

PTEN/MMAC1 mutations in endometrial cancers.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Germline mutations in PTEN are present in Bannayan-Zonana syndrome.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

A novel, rapid, and highly sensitive mass assay for phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) and its application to measure insulin-stimulated PtdIns(3,4,5)P3 production in rat skeletal muscle in vivo

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Frequent inactivation of PTEN/MMAC1 in primary prostate cancer

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

PTEN gene mutations are seen in high-grade but not in low-grade gliomas.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Somatic mutations of PTEN in glioblastoma multiforme.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24850

Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9811831

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.95.23.13513

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

ADS bibcode

1998PNAS...9513513M

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9811831%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

2 references