(Q22253438)

intracellular signal transduction

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Y Wu

1

Y

Wu

1 reference

28 March 2023

D Dowbenko

2

D

Dowbenko

1 reference

28 March 2023

S Spencer

3

S

Spencer

1 reference

28 March 2023

R Laura

4

R

Laura

1 reference

28 March 2023

J Lee

5

J

Lee

1 reference

28 March 2023

Q Gu

6

Q

Gu

1 reference

28 March 2023

L A Lasky

7

L A

Journal of Biological Chemistry

Lasky

1 reference

28 March 2023

language of work or name

English

0 references

publication date

14 July 2000

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published in

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volume

275

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page(s)

21477-85

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issue

28

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cites work

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Pten is essential for embryonic development and tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Protein-protein interactions: PDZ domain networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

PDZ domains: targeting signalling molecules to sub-membranous sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

PDZ proteins organize synaptic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

MAGI-1, a membrane-associated guanylate kinase with a unique arrangement of protein-protein interaction domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

A novel multiple PDZ domain-containing molecule interacting with N-methyl-D-aspartate receptors and neuronal cell adhesion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Crystal structure of a PDZ domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Ion channel targeting in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

PTEN and inherited hamartoma-cancer syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

PTEN: sometimes taking it off can be better than putting it on.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909741199