(Q22254031)

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Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation

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scholarly article

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Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation (English)

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phosphorylation

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Mitogen-activated protein kinase kinase kinase 11

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GOA release 2020-03-11

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GOA release 2020-03-11

author name string

B C Böck

1

author given names

B C

author last names

Böck

1 reference

8 February 2023

P O Vacratsis

2

author given names

P O

author last names

Vacratsis

1 reference

8 February 2023

E Qamirani

3

author given names

E

author last names

Qamirani

1 reference

8 February 2023

K A Gallo

4

author given names

K A

author last names

Gallo

1 reference

8 February 2023

language of work or name

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publication date

12 May 2000

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Journal of Biological Chemistry

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275

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14231-41

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19

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Activation of Raf as a result of recruitment to the plasma membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Rho GTPases and signaling networks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Rho GTPases and the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Transformation activity of Cdc42 requires a region unique to Rho-related proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

CDC42 and FGD1 cause distinct signaling and transforming activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Signals from the Ras, Rac, and Rho GTPases converge on the Pak protein kinase in Rat-1 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Identification of a mouse p21Cdc42/Rac activated kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Structural requirements for PAK activation by Rac GTPases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

A mammalian scaffold complex that selectively mediates MAP kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

A cytoplasmic inhibitor of the JNK signal transduction pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The JIP group of mitogen-activated protein kinase scaffold proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Emerging from the Pak: the p21-activated protein kinase family.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Protein-DNA interactions at a drug-responsive element of the human apolipoprotein A-I gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Carboxyl methylation of the low molecular weight GTP-binding protein G25K: regulation of carboxyl methylation by rhoGDI.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Delineation of the Cdc42/Rac-binding domain of p21-activated kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

Integrin alpha IIb beta 3-mediated translocation of CDC42Hs to the cytoskeleton in stimulated human platelets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

21 January 2018

HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

7 January 2021

based on heuristic

inferred from DOI database lookup

MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.19.14231

7 January 2021

based on heuristic

inferred from DOI database lookup

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