(Q22254126)

negative regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

C Abramovich

1

C

Abramovich

1 reference

30 March 2023

W F Shen

2

W F

Shen

1 reference

30 March 2023

N Pineault

3

N

Pineault

1 reference

30 March 2023

S Imren

4

S

Imren

1 reference

30 March 2023

B Montpetit

5

B

Montpetit

1 reference

30 March 2023

C Largman

6

C

Largman

1 reference

30 March 2023

R K Humphries

7

R K

Journal of Biological Chemistry

Humphries

1 reference

30 March 2023

language of work or name

English

0 references

publication date

25 August 2000

0 references

published in

0 references

volume

275

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page(s)

26172-7

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issue

34

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cites work

The control of trunk Hox specificity and activity by Extradenticle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

The Abd-B-like Hox homeodomain proteins can be subdivided by the ability to form complexes with Pbx1a on a novel DNA target

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

A model for extradenticle function as a switch that changes HOX proteins from repressors to activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

A conserved C-terminal domain in PBX increases DNA binding by the PBX homeodomain and is not a primary site of contact for the YPWM motif of HOXA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Prep1, a novel functional partner of Pbx proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

The subcellular localization of PBX1 and EXD proteins depends on nuclear import and export signals and is modulated by association with PREP1 and HTH

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Control of the nuclear localization of Extradenticle by competing nuclear import and export signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Homeobox genes in hematopoiesis and leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Hox homeobox genes as regulators of normal and leukemic hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Expression of (cac)n/(gtg)n simple repetitive sequences in mRNA of human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

CRM1 is an export receptor for leucine-rich nuclear export signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

An inhibitory switch derepressed by pbx, hox, and Meis/Prep1 partners regulates DNA-binding by pbx1 and E2a-pbx1 and is dispensable for myeloid immortalization by E2a-pbx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

The chimeric oncoproteins E2A-PBX1 and E2A-HLF are concentrated within spherical nuclear domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Selective repression of transcriptional activators by Pbx1 does not require the homeodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

Differential tyrosine phosphorylation of the IFNAR chain of the type I interferon receptor and of an associated surface protein in response to IFN-alpha and IFN-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

7 January 2021

Two versatile eukaryotic vectors permitting epitope tagging, radiolabelling and nuclear localisation of expressed proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

7 January 2021

Members of the meis1 and pbx homeodomain protein families cooperatively bind a cAMP-responsive sequence (CRS1) from bovine CYP17

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

7 January 2021

Functional and cooperative interactions between the homeodomain PDX1, Pbx, and Prep1 factors on the somatostatin promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001323200

7 January 2021