(Q22323542)

English

6-methylsalicylic acid synthase activity

Catalysis of the reaction: acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO(2) + 4 CoA + H(2)O + NADP(+).

  • acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)
  • 6-MSAS activity
  • GO:0050641
  • MSAS activity

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