(Q24290418)

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Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages

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Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages (English)

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protein kinase C zeta

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GOA release 2020-03-11

positive regulation of ERK1 and ERK2 cascade

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GOA release 2020-03-11

Gary W Hunninghake

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object named as

G W Hunninghake

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author name string

M M Monick

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A B Carter

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D M Flaherty

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M W Peterson

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publication date

15 October 2000

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language of work or name

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Journal of Immunology

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165

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8

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4632-9

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PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

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Atypical PKC zeta is activated by ceramide, resulting in coactivation of NF-kappaB/JNK kinase and cell survival

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Lipopolysaccharide binding protein and CD14 in LPS dependent macrophage activation

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7 January 2021

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Intracellular signalling: PDK1--a kinase at the hub of things

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7 January 2021

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Growth factor induced MEK activation is primarily mediated by an activator different from c-raf

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7 January 2021

based on heuristic

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Interleukin-8 receptors R1 and R2 activate mitogen-activated protein kinases and induce c-fos, independent of Ras and Raf-1 in Chinese hamster ovary cells

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7 January 2021

based on heuristic

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Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

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7 January 2021

based on heuristic

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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7 January 2021

based on heuristic

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Differential induction of the mitogen-activated protein kinase pathway by bacterial lipopolysaccharide in cultured monocytes and astrocytes

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7 January 2021

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Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock

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7 January 2021

based on heuristic

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Tumor necrosis factor alpha rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAPK kinase kinase-dependent, c-Raf-1-independent fashion in mouse macrophages

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharide-treated human monocytes

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

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A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Human alveolar macrophages are markedly deficient in REF-1 and AP-1 DNA binding activity

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase C-zeta and phosphoinositide-dependent protein kinase-1 are required for insulin-induced activation of ERK in rat adipocytes

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

inferred from DOI database lookup

RIP2 is a Raf1-activated mitogen-activated protein kinase kinase

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

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Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Multiple pathways control protein kinase C phosphorylation

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

inferred from DOI database lookup

Lipopolysaccharide-induced tumor necrosis factor alpha production by human monocytes involves the raf-1/MEK1-MEK2/ERK1-ERK2 pathway

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

inferred from DOI database lookup

Ras-dependent and -independent pathways target the mitogen-activated protein kinase network in macrophages.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

inferred from DOI database lookup

Lipopolysaccharide and Raf-1 kinase regulate secretory interleukin-1 receptor antagonist gene expression by mutually antagonistic mechanisms

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

H2O2 activates red blood cell K-Cl cotransport via stimulation of a phosphatase

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Lipopolysaccharide-induced NF- κ B Activation and Cytokine Release in Human Alveolar Macrophages Is PKC-independent and TK- and PC-PLC-dependent

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Both Erk and p38 kinases are necessary for cytokine gene transcription

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Partial characterization of a novel mitogen-activated protein kinase/extracellular signal-regulated kinase activator in airway smooth-muscle cells

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Surfactant protein D stimulates phagocytosis of Pseudomonas aeruginosa by alveolar macrophages

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.165.8.4632

7 January 2021

based on heuristic

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Signaling through protein kinase C

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7 January 2021

based on heuristic

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Granulocyte-macrophage colony-stimulating factor in the innate immune response to Pneumocystis carinii pneumonia in mice

1 reference

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based on heuristic

inferred from DOI database lookup

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10.4049/JIMMUNOL.165.8.4632

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