Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q24290437)
Watch
English
ICEBERG: a novel inhibitor of interleukin-1beta generation
scientific article
In more languages
edit
Statements
instance of
scholarly article
0 references
title
ICEBERG: a novel inhibitor of interleukin-1beta generation
(English)
0 references
main subject
interleukins
0 references
Caspase recruitment domain family member 18
1 reference
stated in
GOA release 2020-03-11
inflammatory response
1 reference
stated in
GOA release 2020-03-11
author name string
E W Humke
series ordinal
1
0 references
S K Shriver
series ordinal
2
0 references
M A Starovasnik
series ordinal
3
0 references
W J Fairbrother
series ordinal
4
0 references
V M Dixit
series ordinal
5
0 references
language of work or name
English
0 references
publication date
29 September 2000
0 references
published in
Cell
0 references
volume
103
0 references
page(s)
99-111
0 references
issue
1
0 references
cites work
Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of the interleukin-1 beta converting enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR structure and mutagenesis of the FADD (Mort1) death-effector domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The solution structure of melanoma growth stimulating activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solution structure of the heparin-binding domain of vascular endothelial growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E. coli dnaY gene encodes an arginine transfer RNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-1 beta converting enzyme requires oligomerization for activity of processed forms in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thrombopoietic potential and serial repopulating ability of murine hematopoietic stem cells constitutively expressing interleukin 11.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The modular nature of apoptotic signaling proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CARD domain: a new apoptotic signalling motif
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of death receptor signals by cellular FLIP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The solution structure of FADD death domain. Structural basis of death domain interactions of Fas and FADD
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unresponsiveness of MyD88-deficient mice to endotoxin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Episomal vectors rapidly and stably produce high-titer recombinant retrovirus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MOLMOL: a program for display and analysis of macromolecular structures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR structure of the death domain of the p75 neurotrophin receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of non-bonded parameters on the quality of NMR structures: a new force field for NMR structure calculation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthetic activation of caspases: artificial death switches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An induced proximity model for caspase-8 activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional 13C labeling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase activation: the induced-proximity model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical characteristics of caspases-3, -6, -7, and -8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of CARDIAK, a RIP-like kinase that associates with caspase-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of fas death signals by FLIPs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The fight of viruses against apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional characterization of the prodomain of interleukin-1beta-converting enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and mechanism of interleukin-1 beta converting enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoproteolytic activation of pro-caspases by oligomerization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tolerance to pyrogens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900108-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(00)00108-2
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4914473
OpenCitations bibliographic resource ID
4914473
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4914473
PubMed ID
11051551
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4914473
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit