(Q24291169)

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Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11323411%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2 (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11323411%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

3

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6 November 2019

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J M Cunnick

1

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6 November 2019

L Mei

2

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6 November 2019

J Wu

4

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6 November 2019

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25 April 2001

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6 November 2019

Journal of Biological Chemistry

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6 November 2019

276

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6 November 2019

24380-24387

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6 November 2019

26

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6 November 2019

Shp-2 tyrosine phosphatase: signaling one cell or many

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Protein tyrosine phosphatases in signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Crystal structure of the tyrosine phosphatase SHP-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Activation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain molecule

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

A common requirement for the catalytic activity and both SH2 domains of SHP-2 in mitogen-activated protein (MAP) kinase activation by the ErbB family of receptors. A specific role for SHP-2 in map, but not c-Jun amino-terminal kinase activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

A family of proteins that inhibit signalling through tyrosine kinase receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Engagement of Gab1 and Gab2 in erythropoietin signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Characterization of two SHP-2-associated binding proteins and potential substrates in hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

The Shp-2 tyrosine phosphatase has opposite effects in mediating the activation of extracellular signal-regulated and c-Jun NH2-terminal mitogen-activated protein kinases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Tandem SH2 domains confer high specificity in tyrosine kinase signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Requirement of SHP2 binding to Grb2-associated binder-1 for mitogen-activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Determination of the phosphate content of purified proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

21 January 2018

Regulation of neuregulin-mediated acetylcholine receptor synthesis by protein tyrosine phosphatase SHP2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010275200

7 January 2021

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