(Q24292977)

GOA release 2020-03-11

Mark H Ginsberg

6

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author name string

Kate L Wegener

1

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Anthony W Partridge

2

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Jaewon Han

3

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Andrew R Pickford

4

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Robert C Liddington

5

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Iain D Campbell

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

7

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language of work or name

English

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publication date

12 January 2007

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published in

Cell

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volume

128

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issue

1

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page(s)

171-82

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cites work

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AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

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Calibration of the angular dependence of the amide proton-C alpha proton coupling constants, 3JHN alpha, in a globular protein. Use of 3JHN alpha for identification of helical secondary structure

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MOLMOL: a program for display and analysis of macromolecular structures

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Structural and evolutionary division of phosphotyrosine binding (PTB) domains.

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A coiled-coil structure of the alphaIIbbeta3 integrin transmembrane and cytoplasmic domains in its resting state

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The talin-tail interaction places integrin activation on FERM ground

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A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

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Integrins: bidirectional, allosteric signaling machines

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The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane

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Structural determinants of integrin recognition by talin

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Secondary structure and topology of human interleukin 4 in solution

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Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

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The 2.7 A crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activation

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Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit.

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Protein backbone angle restraints from searching a database for chemical shift and sequence homology

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Optimized set of two-dimensional experiments for fast sequential assignment, secondary structure determination, and backbone fold validation of 13C/15N-labelled proteins.

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Interaction of plasma membrane fibronectin receptor with talin--a transmembrane linkage

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Sequence and domain structure of talin

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Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization

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An interaction between integrin and the talin FERM domain mediates integrin activation but not linkage to the cytoskeleton.

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Latent and active p53 are identical in conformation

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Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

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Genetic, biochemical and structural approaches to talin function

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Membrane-mediated structural transitions at the cytoplasmic face during integrin activation

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7 January 2021

A push-pull mechanism for regulating integrin function

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Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

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7 January 2021

Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits

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Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling

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A genetic analysis of integrin function: Glanzmann thrombasthenia in vitro

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The conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding affinity.

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7 January 2021

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

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The phosphotyrosine binding-like domain of talin activates integrins

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Structure of the active N-terminal domain of Ezrin. Conformational and mobility changes identify keystone interactions

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Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits

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Disabled-2 is a negative regulator of integrin alpha(IIb)beta(3)-mediated fibrinogen adhesion and cell signaling.

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7 January 2021

Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state

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7 January 2021

Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions

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7 January 2021

Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain

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7 January 2021

The hairpin structure of the (6)F1(1)F2(2)F2 fragment from human fibronectin enhances gelatin binding.

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7 January 2021

Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex

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7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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7 January 2021

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

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7 January 2021

Structure and function of the platelet integrin alphaIIbbeta3

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7 January 2021