(Q24296241)

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Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin

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Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin (English)

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protein kinase A regulatory subunit binding

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GOA release 2020-03-11

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based on heuristic

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T cell activation

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Einar M. Aandahl

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object named as

Einar M Aandahl

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Kjetil Taskén

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author name string

Anja Ruppelt

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Randi Mosenden

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Mikaela Grönholm

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Derek Tobin

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Cathrine R Carlson

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Hilde Abrahamsen

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Friedrich W Herberg

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Olli Carpén

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language of work or name

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publication date

15 October 2007

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Journal of Immunology

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179

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8

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5159-68

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Molecular characterization of AKAP149, a novel A kinase anchor protein with a KH domain

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Localization of a novel human A-kinase-anchoring protein, hAKAP220, during spermatogenesis

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Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding

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Alternative roles for CD59.

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Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton

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A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system

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Protein kinase Ctheta: a new essential superstar on the T-cell stage

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ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse

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Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation

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Protein kinase C-theta (PKCtheta): it's all about location, location, location.

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Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

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Negative regulation of T-cell adhesion and activation by CD43

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ICAM-2 redistributed by ezrin as a target for killer cells

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ERM proteins regulate cytoskeleton relaxation promoting T cell–APC conjugation

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AKAP signalling complexes: focal points in space and time

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ERM proteins and merlin: integrators at the cell cortex

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Interaction of radixin with Rho small G protein GDP/GTP exchange protein Dbl

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Positive and negative regulation of T-cell activation through kinases and phosphatases

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Characterization of A-kinase-anchoring disruptors using a solution-based assay

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Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase

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D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain

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Anchoring of protein kinase A facilitates hormone-mediated insulin secretion

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Characterization of S-AKAP84, a novel developmentally regulated A kinase anchor protein of male germ cells

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Phosphorylation of threonine 558 in the carboxyl-terminal actin-binding domain of moesin by thrombin activation of human platelets

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Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits

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Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein

1 reference

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Association of ezrin with intercellular adhesion molecule-1 and -2 (ICAM-1 and ICAM-2). Regulation by phosphatidylinositol 4, 5-bisphosphate

1 reference

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Identification of tethering domains for protein kinase A type Ialpha regulatory subunits on sperm fibrous sheath protein FSC1

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Protein kinase A associates with cystic fibrosis transmembrane conductance regulator via an interaction with ezrin

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Combined spatial and enzymatic regulation of Csk by cAMP and protein kinase a inhibits T cell receptor signaling

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Hierarchy of merlin and ezrin N- and C-terminal domain interactions in homo- and heterotypic associations and their relationship to binding of scaffolding proteins EBP50 and E3KARP.

1 reference

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based on heuristic

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Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.

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Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor

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ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons

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Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

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Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

1 reference

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Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane

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Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

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Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor

1 reference

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CD43 regulation of T cell activation is not through steric inhibition of T cell-APC interactions but through an intracellular mechanism

1 reference

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Layilin, a novel integral membrane protein, is a hyaluronan receptor

1 reference

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Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

1 reference

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based on heuristic

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Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

1 reference

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Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450

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Regulation of in vitro and in vivo T cell activation by CD43

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Location of cAMP-dependent protein kinase type I with the TCR-CD3 complex

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Cbp deficiency alters Csk localization in lipid rafts but does not affect T-cell development

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1 reference

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based on heuristic

inferred from DOI database lookup

AKAP mediated signal transduction

1 reference

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Localized effects of cAMP mediated by distinct routes of protein kinase A.

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FOXP3+CD4+CD25+ Adaptive Regulatory T Cells Express Cyclooxygenase-2 and Suppress Effector T Cells by a Prostaglandin E2-Dependent Mechanism

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Identifiers

10.4049/JIMMUNOL.179.8.5159

1 reference

Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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