(Q24298086)

English

Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1

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scholarly article

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Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1 (English)

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Wiskott-Aldrich syndrome

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Engulfment and cell motility 1

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GOA release 2020-03-11

SH3 domain binding

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GOA release 2020-03-11

author name string

Margaret Porter Scott

1

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Francesca Zappacosta

2

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Eun Young Kim

3

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Roland S Annan

4

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W Todd Miller

5

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language of work or name

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publication date

2 August 2002

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Journal of Biological Chemistry

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277

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28238-46

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31

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Selected glimpses into the activation and function of Src kinase

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https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Cellular functions regulated by Src family kinases

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https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Crystal structure of the Src family tyrosine kinase Hck

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https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Three-dimensional structure of the tyrosine kinase c-Src

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase

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https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

SH2- and SH3-mediated interactions between focal adhesion kinase and Src.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Processive phosphorylation of p130Cas by Src depends on SH3-polyproline interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Reciprocal regulation of Hck activity by phosphorylation of Tyr(527) and Tyr(416). Effect of introducing a high affinity intramolecular SH2 ligand

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

A peptide model system for processive phosphorylation by Src family kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Differential involvement of Src family kinases in Fc gamma receptor-mediated phagocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Fc receptor biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Kinase pathways in chemoattractant-induced degranulation of neutrophils: the role of p38 mitogen-activated protein kinase activated by Src family kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Urokinase receptor-dependent and -independent p56/59(hck) activation state is a molecular switch between myelomonocytic cell motility and adherence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Platelet/polymorphonuclear leukocyte adhesion: a new role for SRC kinases in Mac-1 adhesive function triggered by P-selectin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Adhesion of neutrophils to fibronectin: role of the cd66 antigens

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Soluble E-selectin induces monocyte chemotaxis through Src family tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

How WASP regulates actin polymerization

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https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Waltzing with WASP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Direct analysis and identification of proteins in mixtures by LC/MS/MS and database searching at the low-femtomole level.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Probability-based protein identification by searching sequence databases using mass spectrometry data

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Functional interaction between c-Src and its mitotic target, Sam 68

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Interaction between Wiskott-Aldrich Syndrome protein (WASP) and the Fyn protein-tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The rat homologue of Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) associates with actin filaments, recruits N-WASP from the nucleus, and mediates mobilization of actin from stress fibers in favor of filopodia formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Soluble urokinase receptor promotes cell adhesion and requires tyrosine-92 for activation of p56/59(hck).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Dynamin-mediated internalization of caveolae.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Beyond the RING: CBL proteins as multivalent adapters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Regulating cellular actin assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

DEF-1, a novel Src SH3 binding protein that promotes adipogenesis in fibroblastic cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

hnRNP complexes: composition, structure, and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

WIP regulates N-WASP-mediated actin polymerization and filopodium formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Differential display cloning of a novel rat cDNA (RNB6) that shows high expression in the neonatal brain revealed a member of Ena/VASP family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The tubulin fraternity: alpha to eta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The interaction and colocalization of Sam68 with the splicing-associated factor YT521-B in nuclear dots is regulated by the Src family kinase p59(fyn)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Evidence for SH3 domain directed binding and phosphorylation of Sam68 by Src

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Review: perinucleolar structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

CMS: an adapter molecule involved in cytoskeletal rearrangements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Aberrant expression of TSG101 in Taiwan Chinese breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The role of the adapter molecule SLP-76 in platelet function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Purification and partial amino acid sequencing of a fructosyllysine-specific binding protein from cell membranes of the monocyte-like cell line U937.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Characterization of a protein complex containing spliceosomal proteins SAPs 49, 130, 145, and 155

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Hck Is Activated by Opsonized Zymosan and A23187 in Distinct Subcellular Fractions of Human Granulocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The many faces of Src: multiple functions of a prototypical tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

The integrity of the SH3 binding motif of AFAP-110 is required to facilitate tyrosine phosphorylation by, and stable complex formation with, Src

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Characterization of pp60c-src tyrosine kinase activities using a continuous assay: autoactivation of the enzyme is an intermolecular autophosphorylation process

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Tyrosine phosphorylation of the Wiskott-Aldrich syndrome protein by Lyn and Btk is regulated by CDC42

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202783200

21 January 2018

Identifiers

10.1074/JBC.M202783200

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