(Q24299490)

1

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Estefanía Ugarte-Berzal

2

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María José Terol

3

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Philippe E Van den Steen

4

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Mercedes Hernández del Cerro

5

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Martin Roderfeld

6

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Elke Roeb

7

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José A García-Marco

9

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Angeles García-Pardo

A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis

10

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language of work or name

English

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publication date

17 February 2010

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published in

Cancer Cell

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volume

17

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page(s)

160-72

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issue

2

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cites work

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7 January 2021

Extracellular matrix remodelling: the role of matrix metalloproteinases

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Differential induction of gelatinase B (MMP-9) and gelatinase A (MMP-2) in T lymphocytes upon alpha(4)beta(1)-mediated adhesion to VCAM-1 and the CS-1 peptide of fibronectin

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Mcl-1 is a potential therapeutic target in multiple types of cancer

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7 January 2021

Matrix metalloproteinases and tumor metastasis

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Quantitative analysis of binding of transcription factor complex to biotinylated DNA probe by a streptavidin-agarose pulldown assay

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Gelatinases (MMP-2 and -9) and their natural inhibitors as prognostic indicators in solid cancers

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The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages

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Bone marrow fibroblasts induce expression of PI3K/NF-kappaB pathway genes and a pro-angiogenic phenotype in CLL cells

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Gelatinase B: a tuner and amplifier of immune functions.

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Cell surface association of matrix metalloproteinase-9 (gelatinase B).

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Emerging roles of proteases in tumour suppression

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New functions for the matrix metalloproteinases in cancer progression

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Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases.

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Mechanisms of cytochrome c release from mitochondria

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Fibronectin interaction with α4β1 integrin prevents apoptosis in B cell chronic lymphocytic leukemia: correlation with Bcl-2 and Bax

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Production of matrix metalloproteinase-9 in early stage B-CLL: suppression by interferons

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Constitutive activation of the MAPkinase p38 is critical for MMP-9 production and survival of B-CLL cells on bone marrow stromal cells

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Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis

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7 January 2021

Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro

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Chronic lymphocytic leukemia

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The matrix metalloproteinase 9 (mmp-9) hemopexin domain is a novel gelatin binding domain and acts as an antagonist

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The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors.

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Novel MMP-9 substrates in cancer cells revealed by a label-free quantitative proteomics approach

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Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9)

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The biochemical, biological, and pathological kaleidoscope of cell surface substrates processed by matrix metalloproteinases.

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Prognostic significance of a short sequence insertion in the MCL-1 promoter in chronic lymphocytic leukemia.

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7 January 2021

The role of matrix metalloproteinase 9 in the pathogenesis of chronic lymphocytic leukaemia.

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Metastatic cancer cell

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Matrix metalloproteinases 9 and 10 inhibit protein kinase C-potentiated, p53-mediated apoptosis

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Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment

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7 January 2021

Matrix metalloproteinase-9 inhibition down-regulates radiation-induced nuclear factor-kappa B activity leading to apoptosis in breast tumors

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7 January 2021

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis

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7 January 2021

Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

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CLL, but not normal, B cells are dependent on autocrine VEGF and alpha4beta1 integrin for chemokine-induced motility on and through endothelium

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7 January 2021

Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding

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7 January 2021

MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by 4beta1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration

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7 January 2021

Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity

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7 January 2021

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

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7 January 2021

Matrix metalloproteinase-9 is up-regulated by CCL21/CCR7 interaction via extracellular signal-regulated kinase-1/2 signaling and is involved in CCL21-driven B-cell chronic lymphocytic leukemia cell invasion and migration

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7 January 2021

4 1 integrin and 190-kDa CD44v constitute a cell surface docking complex for gelatinase B/MMP-9 in chronic leukemic but not in normal B cells

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7 January 2021

The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes.

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7 January 2021

Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia

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7 January 2021

The microenvironment in mature B-cell malignancies: a target for new treatment strategies

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7 January 2021

The chemokine receptor CCR7 and alpha4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes

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7 January 2021

Hemopexin domains as multifunctional liganding modules in matrix metalloproteinases and other proteins

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7 January 2021

Anti-CCR7 monoclonal antibodies as a novel tool for the treatment of chronic lymphocyte leukemia.

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7 January 2021

SFK-STAT pathway: an alternative and important way to malignancies

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7 January 2021

B-cell chronic lymphocytic leukemia: a bird of a different feather

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7 January 2021