(Q24299873)

GOA release 2020-03-11

Raptor Dmel_CG4320

1 reference

GOA release 2020-03-11

author

Hediye Erdjument-Bromage

6

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Paul Tempst

7

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Do-Hyung Kim

object named as

Do-Hyung Kim

3

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David M. Sabatini

8

object named as

David M Sabatini

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author name string

D D Sarbassov

1

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Siraj M Ali

2

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David A Guertin

4

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Robert R Latek

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

5

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language of work or name

English

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publication date

27 July 2004

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published in

Current Biology

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volume

14

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page(s)

1296-302

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issue

14

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Regulation of amino acid-sensitive TOR signaling by leucine analogues in adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Gene ste20 controls amiloride sensitivity and fertility in Schizosaccharomyces pombe.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Paxillin and focal adhesion signalling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Protein kinase C alpha (PKC alpha): regulation and biological function

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Replacement of Ser657 of protein kinase C-alpha by alanine leads to premature down regulation after phorbol-ester-induced translocation to the membrane

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Lentivirus-delivered stable gene silencing by RNAi in primary cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021

Metabolic regulation by leucine of translation initiation through the mTOR-signaling pathway by pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.06.054

7 January 2021