(Q24302243)

Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

GOA release 2020-03-11

1 reference

protein domain specific binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Mikako Shirouzu

8

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Takayoshi Matsuda

Takayoshi Matsuda

12

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Osamu Ohara

Osamu Ohara

21

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Shigeyuki Yokoyama

Shigeyuki Yokoyama

23

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Takaho Terada

17

Takaho Terada

0 references

Takanori Kigawa

2

Takanori Kigawa

0 references

Seizo Koshiba

3

Seizo Koshiba

0 references

Ayako N Sakamoto

6

Ayako Sakamoto

0 references

Tetsuo Takagi

7

Tetsuo Takagi

0 references

Takashi Yabuki

9

Takashi Yabuki

0 references

Emi Nunokawa

10

Emi Nunokawa

0 references

Eiko Seki

11

Eiko Seki

0 references

Masaaki Aoki

13

Masaaki Aoki

0 references

Takahiro Nagase

18

Takahiro Nagase

0 references

Yukako Miyata

14

Yukako Miyata

0 references

Makoto Inoue

16

Makoto Inoue

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author name string

Kohei Saito

1

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Kazuo Sato

4

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Yo Matsuo

5

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Noriko Hirakawa

15

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Reiko Kikuno

19

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Manabu Nakayama

20

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Akiko Tanaka

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

22

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language of work or name

English

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publication date

September 2004

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published in

Structure

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volume

12

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page(s)

1719-28

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issue

9

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cites work

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Characterisation of fission yeast alp11 mutants defines three functional domains within tubulin-folding cofactor B

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Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12-q13

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MOLMOL: a program for display and analysis of macromolecular structures

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Sequence homologies between four cytoskeleton-associated proteins.

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WW and SH3 domains, two different scaffolds to recognize proline-rich ligands

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Can we infer peptide recognition specificity mediated by SH3 domains?

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Cell-free production and stable-isotope labeling of milligram quantities of proteins

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Multidimensional heteronuclear nuclear magnetic resonance of proteins

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of actin assembly

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

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Missing pieces in the NF-kappaB puzzle

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Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde

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Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

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7 January 2021

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

1 reference

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7 January 2021

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

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7 January 2021

The structural basis for the recognition of diverse receptor sequences by TRAF2

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7 January 2021

TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

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7 January 2021

The high-resolution, three-dimensional solution structure of human interleukin-4 determined by multidimensional heteronuclear magnetic resonance spectroscopy

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Protein backbone angle restraints from searching a database for chemical shift and sequence homology

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Preparation of Escherichia coli cell extract for highly productive cell-free protein expression

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Structural basis for self-association and receptor recognition of human TRAF2

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7 January 2021

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

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7 January 2021

Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

1 reference

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7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2004.07.012

7 January 2021

Identification of the familial cylindromatosis tumour-suppressor gene

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7 January 2021

Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan

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7 January 2021

Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

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7 January 2021

X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

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7 January 2021

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

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7 January 2021

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

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7 January 2021

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

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7 January 2021

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

1 reference

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7 January 2021

Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2004.07.012

7 January 2021

A novel, specific interaction involving the Csk SH3 domain and its natural ligand

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7 January 2021

Tumor necrosis factor receptor-associated factors (TRAFs)

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7 January 2021

Crystallographic analysis of CD40 recognition and signaling by human TRAF2

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7 January 2021

Molecular basis for CD40 signaling mediated by TRAF3

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7 January 2021

Purification and Analysis of Authentic CLIP-170 and Recombinant Fragments

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7 January 2021

Crystal structure of the cytoskeleton-associated protein glycine-rich (CAP-Gly) domain

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7 January 2021

Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).

1 reference

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A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha

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7 January 2021

Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin

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7 January 2021

Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p

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7 January 2021

Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules

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7 January 2021

HUGE: a database for human large proteins identified in the Kazusa cDNA sequencing project

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Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

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7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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7 January 2021

The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2004.07.012

7 January 2021

The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.STR.2004.07.012

7 January 2021