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Tumor suppressor LATS1 is a negative regulator of oncogene YAP
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scholarly article
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title
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
(English)
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main subject
Yes1 associated transcriptional regulator
1 reference
stated in
GOA release 2020-03-11
hippo signaling
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stated in
GOA release 2020-03-11
author name string
Yawei Hao
series ordinal
1
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Alex Chun
series ordinal
2
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Kevin Cheung
series ordinal
3
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Babak Rashidi
series ordinal
4
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Xiaolong Yang
series ordinal
5
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language of work or name
English
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publication date
29 February 2008
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published in
Journal of Biological Chemistry
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volume
283
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page(s)
5496-509
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issue
9
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cites work
Integrins in regulation of tissue development and function.
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
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inferred from DOI database lookup
Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
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Negative regulators of cyclin-dependent kinases and their roles in cancers
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7 January 2021
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Control of dendritic branching and tiling by the Tricornered-kinase/Furry signaling pathway in Drosophila sensory neurons.
1 reference
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7 January 2021
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Control of cell proliferation and apoptosis by mob as tumor suppressor, mats
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Crossref
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7 January 2021
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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
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inferred from DOI database lookup
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
1 reference
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AKT/PKB signaling: navigating downstream
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7 January 2021
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Elucidation of a universal size-control mechanism in Drosophila and mammals
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Crossref
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7 January 2021
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The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway.
1 reference
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7 January 2021
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Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death
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Crossref
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7 January 2021
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The Drosophila RASSF homolog antagonizes the hippo pathway
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7 January 2021
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Cellular signaling by fibroblast growth factor receptors
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Platelet-derived growth factor receptor (PDGFR): a target for anticancer therapeutics.
1 reference
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Phosphorylation of human microtubule-associated protein tau by protein kinases of the AGC subfamily
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7 January 2021
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Centrosome-associated NDR kinase regulates centrosome duplication
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Shedding light on Merlin's wizardry
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Putative tumor suppressor Lats2 induces apoptosis through downregulation of Bcl-2 and Bcl-x(L).
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
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Crossref
reference URL
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retrieved
7 January 2021
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Integrins: bidirectional, allosteric signaling machines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
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7 January 2021
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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis
1 reference
stated in
Crossref
reference URL
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Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Delineation of a Fat tumor suppressor pathway
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
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inferred from DOI database lookup
The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
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inferred from DOI database lookup
Mechanisms of specificity in protein phosphorylation
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stated in
Crossref
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Filling out the Hippo pathway
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
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inferred from DOI database lookup
Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human homologue of Drosophila lats, LATS1, negatively regulate growth by inducing G(2)/M arrest or apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lats2, a putative tumor suppressor, inhibits G1/S transition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physical interaction with Yes-associated protein enhances p73 transcriptional activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of cell growth by conditional expression of kpm, a human homologue of Drosophila warts/lats tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hippo signaling in organ size control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
WW domains provide a platform for the assembly of multiprotein networks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RASSF4/AD037 is a potential ras effector/tumor suppressor of the RASSF family.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defining the role of prolactin as an invasion suppressor hormone in breast cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
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7 January 2021
based on heuristic
inferred from DOI database lookup
Beta4 integrin is a transforming molecule that unleashes Met tyrosine kinase tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substrate specificity analysis of protein kinase complex Dbf2-Mob1 by peptide library and proteome array screening
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The RASSF1A tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M709037200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1074/JBC.M709037200
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
196258
Fatcat ID
release_omlgwxm5vrdqvomjb54zmifmqe
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/omlgwxm5vrdqvomjb54zmifmqe
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
196258
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
196258
PubMed ID
18158288
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
196258
ResearchGate publication ID
5691600
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