(Q24307014)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

1 reference

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Jing Tan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Puay Leng Lee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Zhimei Li

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Xia Jiang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Yaw Chyn Lim

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Qiang Yu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

1 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

459-471

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

Small-molecule inhibitors of PDK1.

16 January 2020

cites work

1 reference

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7 January 2021

"New"-clear functions of PDK1: beyond a master kinase in the cytosol?

1 reference

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7 January 2021

A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins

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7 January 2021

The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.

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7 January 2021

Species- and cell type-specific requirements for cellular transformation

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7 January 2021

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

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7 January 2021

Defining the role of mTOR in cancer

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7 January 2021

DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications

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7 January 2021

AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer

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7 January 2021

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

1 reference

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7 January 2021

The tumor suppressor PP2A Abeta regulates the RalA GTPase

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7 January 2021

CIP2A inhibits PP2A in human malignancies

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7 January 2021

A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation

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7 January 2021

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

1 reference

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7 January 2021

APC is essential for targeting phosphorylated beta-catenin to the SCFbeta-TrCP ubiquitin ligase.

1 reference

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7 January 2021

From promiscuity to precision: protein phosphatases get a makeover

1 reference

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7 January 2021

Multiple pathways regulated by the tumor suppressor PP2A in transformation

1 reference

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7 January 2021

ONCOMINE: a cancer microarray database and integrated data-mining platform

1 reference

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7 January 2021

Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Identification of specific PP2A complexes involved in human cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Myc deletion rescues Apc deficiency in the small intestine

1 reference

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7 January 2021

The cancer biomarker problem

1 reference

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7 January 2021

Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis

1 reference

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7 January 2021

GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer

1 reference

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7 January 2021

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

1 reference

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7 January 2021

Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

1 reference

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7 January 2021

mTOR and cancer: insights into a complex relationship

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Current development of mTOR inhibitors as anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

mTOR and cancer therapy

1 reference

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7 January 2021

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

1 reference

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7 January 2021

Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Regulation of phosphorylation of Thr-308 of Akt, cell proliferation, and survival by the B55alpha regulatory subunit targeting of the protein phosphatase 2A holoenzyme to Akt.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression

1 reference

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7 January 2021

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

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7 January 2021

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

1 reference

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7 January 2021

Alterations of the PPP2R1B gene in human lung and colon cancer

1 reference

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7 January 2021

Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

1 reference

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7 January 2021

Enumeration of the simian virus 40 early region elements necessary for human cell transformation

1 reference

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7 January 2021

Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers

1 reference

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7 January 2021

Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

1 reference

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7 January 2021

3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2010.10.021

7 January 2021

10.1016/J.CCR.2010.10.021

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

4143087

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21075311%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

4143087

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

4143087