(Q24313251)

1

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Tsuyoshi Miyazaki

2

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Cecile Itzstein

3

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Enkhtsetseg Purev

4

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William C Horne

5

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Roland Baron

Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation

6

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language of work or name

English

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publication date

December 2006

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published in

FEBS Journal

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volume

273

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page(s)

5442-56

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issue

23

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cites work

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Epidermal growth factor modulates tyrosine phosphorylation of p130Cas. Involvement of phosphatidylinositol 3'-kinase and actin cytoskeleton

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motif

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Negative regulation of Lck by Cbl ubiquitin ligase

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

The adapter type protein CMS/CD2AP binds to the proto-oncogenic protein c-Cbl through a tyrosine phosphorylation-regulated Src homology 3 domain interaction

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Src kinase activity is essential for osteoclast function

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Three-dimensional structure of the tyrosine kinase c-Src

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

Regulation of cytochrome c oxidase activity by c-Src in osteoclasts

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

A simplified system for generating recombinant adenoviruses

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2006.05535.X

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

20 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

EGF receptor binding and transformation by v-cbl is ablated by the introduction of a loss-of-function mutation from the Caenorhabditis elegans sli-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

SH3P2 in complex with Cbl and Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Identification of the potential active site of the signal peptidase SipS of Bacillus subtilis. Structural and functional similarities with LexA-like proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Selective activation of T cell kinase p56lck by Herpesvirus saimiri protein tip.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Cbl: many adaptations to regulate protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Negative receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Recognition and specificity in protein tyrosine kinase-mediated signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Critical residues in an SH3 domain from Sem-5 suggest a mechanism for proline-rich peptide recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Structural basis for the binding of proline-rich peptides to SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

The Cbl family proteins: ring leaders in regulation of cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

A functional link between dynamin and the actin cytoskeleton at podosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

SH2- and SH3-mediated interactions between focal adhesion kinase and Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

An essential role of ubiquitination in Cbl-mediated negative regulation of the Src-family kinase Fyn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

7 January 2021

Catalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

7 January 2021

Deletion of the gene encoding c-Cbl alters the ability of osteoclasts to migrate, delaying resorption and ossification of cartilage during the development of long bones

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

7 January 2021

Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

7 January 2021

Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

7 January 2021

The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine Kinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

7 January 2021

Biochemical basis for the requirement of kinase activity for Cbl-dependent ubiquitinylation and degradation of a target tyrosine kinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

7 January 2021

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

7 January 2021

Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

7 January 2021

The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2006.05535.X

7 January 2021