(Q24313552)

2

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Vignesh Alamanda

3

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Roberta Pireddu

4

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Daniel Pernazza

5

0 references

Said Sebti

6

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Nicholas Lawrence

7

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Srikumar Chellappan

Molecular Cancer Therapeutics

8

0 references

language of work or name

English

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publication date

December 2010

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published in

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volume

9

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page(s)

3330-41

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issue

12

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cites work

Deregulated E2F transcriptional activity in autonomously growing melanoma cells

1 reference

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Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation

19 March 2017

1 reference

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Increased gene copy number of the transcription factor E2F1 in malignant melanoma

19 March 2017

1 reference

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Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

19 March 2017

1 reference

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Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

19 March 2017

1 reference

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Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

19 March 2017

1 reference

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Distinct sets of genetic alterations in melanoma

19 March 2017

1 reference

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A simple technique for quantitation of low levels of DNA damage in individual cells

7 April 2017

1 reference

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The E2F transcription factor is a cellular target for the RB protein

7 April 2017

1 reference

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Treatment for metastatic malignant melanoma: old drugs and new strategies

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

RNA silencing of Mcl-1 enhances ABT-737-mediated apoptosis in melanoma: role for a caspase-8-dependent pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice.

27 September 2017

1 reference

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Treatment approaches for advanced cutaneous melanoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Systemic therapy for metastatic malignant melanoma--from deeply disappointing to bright future?

27 September 2017

1 reference

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Overcoming apoptosis deficiency of melanoma-hope for new therapeutic approaches

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Combined treatment with Ad-hTRAIL and DTIC or SAHA is associated with increased mitochondrial-mediated apoptosis in human melanoma cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Rb/E2F: a two-edged sword in the melanocytic system

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Treatment of metastatic malignant melanoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Re-evaluating the role of dacarbazine in metastatic melanoma: what have we learned in 30 years?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Issues in the epidemiology of melanoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

27 September 2017

1 reference

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Single-agent DTIC versus combination chemotherapy with or without immunotherapy in metastatic melanoma: a meta-analysis of 3273 patients from 20 randomized trials

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Rb function in cell-cycle regulation and apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

A Detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

27 September 2017

Cancer statistics, 2003.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Dosage and cycle effects of dacarbazine (DTIC) and fotemustine on O6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Mcl-1 is required for melanoma cell resistance to anoikis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Plitidepsin has a dual effect inhibiting cell cycle and inducing apoptosis via Rac1/c-Jun NH2-terminal kinase activation in human melanoma cells.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058238

Expression of apoptosis regulators in cutaneous malignant melanoma

29 November 2018

1 reference

12 December 2020

Melanomas, from the cell cycle point of view (Review)

1 reference

12 December 2020

Myeloid leukemia-1 expression in benign and malignant melanocytic lesions

1 reference

12 December 2020

BRAF and RAS mutations in human lung cancer and melanoma

1 reference

12 December 2020

Antiapoptotic bcl-2 and bcl-xL in advanced malignant melanoma

1 reference

12 December 2020

Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma

1 reference

12 December 2020