(Q24315871)

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A rare mRNA variant of the human lymphocyte-specific protein tyrosine kinase LCK gene with intron B retention and exon 7 skipping encodes a putative protein with altered SH3-dependent molecular interactions

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16107303%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

A rare mRNA variant of the human lymphocyte-specific protein tyrosine kinase LCK gene with intron B retention and exon 7 skipping encodes a putative protein with altered SH3-dependent molecular interactions (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16107303%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

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molecular interaction

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Rodolphe Guinamard

2

1 reference

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5 January 2020

Patrick Lécine

4

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5 January 2020

7

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5 January 2020

author name string

Solange Nervi

1

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5 January 2020

Bénédicte Delaval

3

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5 January 2020

Bernard Vialettes

5

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5 January 2020

Philippe Naquet

6

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5 January 2020

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publication date

1 October 2005

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5 January 2020

1 reference

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5 January 2020

359

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5 January 2020

18-25

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5 January 2020

Exon mutations uncouple 5' splice site selection from U1 snRNA pairing.

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Quality control of messenger ribonucleoprotein particles in the nucleus and at the pore

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of adaptor proteins in lymphocyte activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

The exon 7-spliced Lck isoform in T lymphocytes: a potential regulator of p56lck signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulatory intramolecular association in a tyrosine kinase of the Tec family

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

A single base mutation in the 5' splice site of intron 7 of the lck gene is responsible for the deletion of exon 7 in lck mRNA of the JCaM1 cell line

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

The distinct capacity of Fyn and Lck to phosphorylate Sam68 in T cells is essentially governed by SH3/SH2-catalytic domain linker interactions

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Signalling through CD28 T-cell activation pathway involves an inositol phospholipid-specific phospholipase C activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Negative regulation of Lck by Cbl ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

A Zn2+ ion links the cytoplasmic tail of CD4 and the N-terminal region of Lck

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for p56(lck) tyrosine kinase activation in Th subset differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

A catalogue of splice junction sequences

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Distribution and consensus of branch point signals in eukaryotic genes: a computerized statistical analysis

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of p56lck and p59fyn tyrosine kinases and CD45 protein tyrosine phosphatase in T-cell development and clonal selection

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the two promoters of the human lck gene: differential accumulation of two classes of lck transcripts in T cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective expression of alternative lck mRNAs in human malignant cell lines

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective expression of p56lck in an infant with severe combined immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

No association between lck gene polymorphisms and protein level in type 1 diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Dysregulation of the protein tyrosine kinase LCK in lymphoproliferative disorders and in other neoplasias

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific deficiency of p56lck expression in T lymphocytes from type 1 diabetic patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

A molecular framework for two-step T cell signaling: Lck Src homology 3 mutations discriminate distinctly regulated lipid raft reorganization events

1 reference

https://api.crossref.org/works/10.1016%2FJ.GENE.2005.06.018

7 January 2021

based on heuristic

inferred from DOI database lookup

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