(Q24317173)

English

Slow-channel myasthenic syndrome caused by enhanced activation, desensitization, and agonist binding affinity attributable to mutation in the M2 domain of the acetylcholine receptor alpha subunit

scientific article

Slow-Channel Myasthenic Syndrome Caused By Enhanced Activation, Desensitization, and Agonist Binding Affinity Attributable to Mutation in the M2 Domain of the Acetylcholine Receptor α Subunit

In more languages

Statements

scholarly article

0 references

Slow-channel myasthenic syndrome caused by enhanced activation, desensitization, and agonist binding affinity attributable to mutation in the M2 domain of the acetylcholine receptor alpha subunit (English)

0 references

Slow-Channel Myasthenic Syndrome Caused By Enhanced Activation, Desensitization, and Agonist Binding Affinity Attributable to Mutation in the M2 Domain of the Acetylcholine Receptor α Subunit (English)

0 references

1 reference

based on heuristic

inferred from title

Cholinergic receptor nicotinic alpha 1 subunit

1 reference

GOA release 2020-03-11

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

1 reference

GOA release 2020-03-11

desensitization

1 reference

based on heuristic

inferred from title

Margherita Milone

1

object named as

Margherita Milone

0 references

author name string

M Milone

1

0 references

H L Wang

2

0 references

K Ohno

3

0 references

T Fukudome

4

0 references

J N Pruitt

5

0 references

N Bren

6

0 references

S M Sine

7

0 references

A G Engel

8

0 references

Hai-Long Wang

2

0 references

Kinji Ohno

3

0 references

Takayasu Fukudome

4

0 references

J. Ned Pruitt

5

0 references

Nina Bren

6

0 references

Steven M. Sine

7

0 references

Andrew G. Engel

8

0 references

language of work or name

0 references

publication date

1 August 1997

0 references

Journal of Neuroscience

0 references

17

0 references

5651-65

0 references

5651-5665

0 references

15

0 references

Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Torpedo acetylcholine receptors expressed in mouse fibroblasts. Single channel current kinetics reveal distinct agonist binding affinities

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltage dependence of mouse acetylcholine receptor gating: different charge movements in di-, mono- and unliganded receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A beta-subunit mutation in the acetylcholine receptor channel gate causes severe slow-channel syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A newly recognized congenital myasthenic syndrome attributed to a prolonged open time of the acetylcholine-induced ion channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patch-clamp analysis of the properties of acetylcholine receptor channels at the normal human endplate

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congenital myasthenic syndromes: II. Syndrome attributed to abnormal interaction of acetylcholine with its receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary structure of the human muscle acetylcholine receptor. cDNA cloning of the gamma and epsilon subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Data transformations for improved display and fitting of single-channel dwell time histograms

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parental somatic and germ-line mosaicism for a multiexon deletion with unusual endpoints in a type III collagen (COL3A1) allele produces Ehlers-Danlos syndrome type IV in the heterozygous offspring

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructural localization of the acetylcholine receptor in myasthenia gravis and in its experimental autoimmune model

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis of the different gating kinetics of fetal and adult acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of acetylcholine receptors on clonal mammalian BC3H-1 cells by high concentrations of agonist.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conserved tyrosines in the alpha subunit of the nicotinic acetylcholine receptor stabilize quaternary ammonium groups of agonists and curariform antagonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of acetylcholine receptors on clonal mammalian BC3H-1 cells by low concentrations of agonist.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the stochastic properties of single ion channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congenital myasthenic syndrome caused by decreased agonist binding affinity due to a mutation in the acetylcholine receptor epsilon subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and sequence analysis of calf cDNA and human genomic DNA encoding alpha-subunit precursor of muscle acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perfection of a synaptic receptor: kinetics and energetics of the acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

End-plate acetylcholine receptor deficiency due to nonsense mutations in the epsilon subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The permeation pathway of neurotransmitter-gated ion channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acetylcholine receptor at 9 A resolution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A muscle acetylcholine receptor is expressed in the human cerebellar medulloblastoma cell line TE671.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new myasthenic syndrome with end-plate acetylcholinesterase deficiency, small nerve terminals, and reduced acetylcholine release

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human medulloblastoma cell line TE671 expresses a muscle-like acetylcholine receptor. Cloning of the alpha-subunit cDNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The end of the (cell) line: methods for the study of apoptosis in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide sequence of human muscle acetylcholine receptor beta-subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium permeability increase of endplate channels in rat muscle during postnatal development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of a nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A suggested nomenclature for designating mutations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of recombinant mouse acetylcholine receptors by acetylcholine, carbamylcholine and tetramethylammonium

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between membrane excitability and single channel open-close kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of the acetylcholine receptor alpha subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congenital myasthenic syndromes: I. Deficiency and short open-time of the acetylcholine receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional differences among nonerythroid anion exchangers expressed in a transfected human cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/9221765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.17-15-05651.1997

0 references

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q24317173&oldid=1962854355"