(Q24320223)

English

Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

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scholarly article

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Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src (English)

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PTK2 protein tyrosine kinase 2

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GOA release 2020-03-11

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based on heuristic

inferred from title

author name string

D D Schlaepfer

1

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T Hunter

2

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language of work or name

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publication date

16 May 1997

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Journal of Biological Chemistry

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272

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13189-95

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20

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Calcium influx induces neurite growth through a Src-Ras signaling cassette

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https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

The adaptor protein Shc couples a class of integrins to the control of cell cycle progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway

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https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific and redundant roles of Src and Fyn in organizing the cytoskeleton.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Three-dimensional structure of the tyrosine kinase c-Src

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https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

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https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily

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https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

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https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase

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https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Ras activation is necessary for integrin-mediated activation of extracellular signal-regulated kinase 2 and cytosolic phospholipase A2 but not for cytoskeletal organization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-mediated activation of MEK and mitogen-activated protein kinase is independent of Ras [corrected].

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. Dissociation from tyrosine phosphorylation of p125 focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Diphtheria toxin-mediated ablation of parietal cells in the stomach of transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of cell motility by mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrins and signal transduction pathways: the road taken

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https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Csk suppression of Src involves movement of Csk to sites of Src activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrins: emerging paradigms of signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Focal adhesions, contractility, and signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.20.13189

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.272.20.13189

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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