(Q24321902)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0071886

5-hydroxytryptamine receptor 2C

1 reference

5-hydroxytryptamine receptor 2B

1 reference

5-hydroxytryptamine receptor 2A

1 reference

positive regulation of ERK1 and ERK2 cascade

1 reference

Naunyn-Schmiedeberg's Archives of Pharmacology

1 reference

Christopher S Knauer

1

0 references

Jeffrey E Campbell

series ordinal

2

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Christopher L Chio

series ordinal

3

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Lawrence W Fitzgerald

series ordinal

4

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language of work or name

English

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publication date

May 2009

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published in

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volume

379

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page(s)

461-71

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issue

5

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exact match

https://scigraph.springernature.com/pub.10.1007/s00210-008-0378-4

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cites work

The pharmacology and distribution of human 5-hydroxytryptamine2B (5-HT2B) receptor gene products: comparison with 5-HT2A and 5-HT2C receptors

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00210-008-0378-4

Messenger RNA editing of the human serotonin 5-HT2C receptor

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00210-008-0378-4

[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00210-008-0378-4

New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

21 January 2018

1 reference

12 December 2020

Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors

1 reference

12 December 2020

5-HT2 receptor subtypes: a family re-united?

1 reference

12 December 2020

Activation of extracellular-regulated kinase by 5-hydroxytryptamine(2A) receptors in PC12 cells is protein kinase C-independent and requires calmodulin and tyrosine kinases

1 reference

12 December 2020

Mechanisms of 5-hydroxytryptamine(2A) receptor activation of the mitogen-activated protein kinase pathway in vascular smooth muscle.

1 reference

12 December 2020

The evasive nature of drug efficacy: implications for drug discovery

1 reference

12 December 2020

Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors

1 reference

12 December 2020

A multi-well filtration assay for quantitation of inositol phosphates in biological samples

1 reference

12 December 2020

1 reference

12 December 2020

Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells.

1 reference

12 December 2020

Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus.

1 reference

12 December 2020

Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells

1 reference

12 December 2020

Aortic recognition sites for serotonin (5HT) are coupled to phospholipase C and modulate phosphatidylinositol turnover

1 reference

12 December 2020

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

1 reference

12 December 2020

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

12 December 2020

Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine

1 reference

12 December 2020

ERK2: a logical AND gate critical for drug-induced plasticity?

1 reference

12 December 2020

Integration of mitogen-activated protein kinase kinase activation in vascular 5-hydroxytryptamine2A receptor signal transduction

1 reference

12 December 2020

Histamine antagonizes serotonin and growth factor-induced mitogen-activated protein kinase activation in bovine tracheal smooth muscle cells

1 reference

12 December 2020

Plasticity within striatal direct pathway neurons after neonatal dopamine depletion is mediated through a novel functional coupling of serotonin 5-HT2 receptors to the ERK 1/2 map kinase pathway

1 reference

12 December 2020

Serotonin stimulates phospholipase A2 and the release of arachidonic acid in hippocampal neurons by a type 2 serotonin receptor that is independent of inositolphospholipid hydrolysis

1 reference

12 December 2020

Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2.

1 reference

12 December 2020

Selective 5HT-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex.

1 reference

12 December 2020

RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity

1 reference

12 December 2020

Functional selectivity of D2 receptor ligands in a Chinese hamster ovary hD2L cell line: evidence for induction of ligand-specific receptor states

1 reference

12 December 2020

Differential activation of Gq/11 and Gi(3) proteins at 5-hydroxytryptamine(2C) receptors revealed by antibody capture assays: influence of receptor reserve and relationship to agonist-directed trafficking

1 reference

12 December 2020

High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action

1 reference

12 December 2020

5-HT(2A) receptors stimulate mitogen-activated protein kinase via H(2)O(2) generation in rat renal mesangial cells

1 reference

12 December 2020

Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors

1 reference

12 December 2020

Ras involvement in signal transduction by the serotonin 5-HT2B receptor

1 reference

12 December 2020

Functional selectivity through protean and biased agonism: who steers the ship?

1 reference

12 December 2020

Pharmacological characterisation of human 5-HT2 receptor subtypes

1 reference

12 December 2020