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Mdm2 promotes the rapid degradation of p53
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title
Mdm2 promotes the rapid degradation of p53
(English)
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main subject
MDM2 proto-oncogene
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stated in
GOA release 2020-03-11
regulation of protein catabolic process
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stated in
GOA release 2020-03-11
author name string
Y Haupt
series ordinal
1
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R Maya
series ordinal
2
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A Kazaz
series ordinal
3
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M Oren
series ordinal
4
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language of work or name
English
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publication date
15 May 1997
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published in
Nature
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volume
387
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issue
6630
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page(s)
296-9
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cites work
Viruses and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53-mdm2 autoregulatory feedback loop: a paradigm for the regulation of growth control by p53?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 gene is induced in response to UV light in a p53-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the Cellular p53 Tumor Antigen in Teratocarcinoma Cells and Their Differentiated Progeny
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation of p53 function: Steiner Award Lecture.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between the retinoblastoma protein and the oncoprotein MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F387296A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/387296A0
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
279766
Dimensions Publication ID
1004301257
0 references
OpenCitations bibliographic resource ID
279766
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
279766
PubMed publication ID
9153395
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
279766
ResearchGate publication ID
14065954
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