(Q24329080)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damage (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

0 references

Marta Vázquez-Cedeira

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

Alejandro Carrillo-Jiménez

7 March 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Pedro A. Lazo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

author name string

Inmaculada López-Sánchez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Alberto Valbuena

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Jyoti Khadake

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Marta Sanz-García

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

language of work or name

English

0 references

publication date

31 January 2014

1 reference

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7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

volume

588

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

page(s)

692-700

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

issue

5

1 reference

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Blinded by the Light: The Growing Complexity of p53

7 March 2020

cites work

1 reference

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The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.

21 January 2018

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p53 Stabilization and accumulation induced by human vaccinia-related kinase 1

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p53 downregulates its activating vaccinia-related kinase 1, forming a new autoregulatory loop

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Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

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The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53

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Characterization of three paralogous members of the Mammalian vaccinia related kinase family

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The protein kinase complement of the human genome

21 January 2018

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The conserved kinase NHK-1 is essential for mitotic progression and unifying acentrosomal meiotic spindles in Drosophila melanogaster

21 January 2018

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Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly

21 January 2018

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Genome-wide analysis of germ cell proliferation in C.elegans identifies VRK-1 as a key regulator of CEP-1/p53

21 January 2018

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Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

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c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK)

21 January 2018

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Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK

21 January 2018

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Mitotic histone H3 phosphorylation by vaccinia-related kinase 1 in mammalian cells.

21 January 2018

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Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities

21 January 2018

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Macro histone H2A1.2 (macroH2A1) protein suppresses mitotic kinase VRK1 during interphase

21 January 2018

1 reference

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HnRNP A1 phosphorylated by VRK1 stimulates telomerase and its binding to telomeric DNA sequence

21 January 2018

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21 January 2018

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Downregulation of VRK1 by p53 in response to DNA damage is mediated by the autophagic pathway

21 January 2018

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Alteration of the VRK1-p53 autoregulatory loop in human lung carcinomas

21 January 2018

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Roles of VRK1 as a new player in the control of biological processes required for cell division.

21 January 2018

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Human VRK1 is an early response gene and its loss causes a block in cell cycle progression

21 January 2018

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VRK1 signaling pathway in the context of the proliferation phenotype in head and neck squamous cell carcinoma.

21 January 2018

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Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas.

21 January 2018

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Molecular genetic analysis of VRK1 in mammary epithelial cells: depletion slows proliferation in vitro and tumor growth and metastasis in vivo

21 January 2018

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Mice deficient in the serine/threonine protein kinase VRK1 are infertile due to a progressive loss of spermatogonia

21 January 2018

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21 January 2018

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The kinase VRK1 is required for normal meiotic progression in mammalian oogenesis.

21 January 2018

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Defective folliculogenesis in female mice lacking Vaccinia-related kinase 1.

21 January 2018

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Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentation

21 January 2018

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Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations

21 January 2018

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Substrate profiling of human vaccinia-related kinases identifies coilin, a Cajal body nuclear protein, as a phosphorylation target with neurological implications

21 January 2018

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Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1.

21 January 2018

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Sensitivity of the kinase activity of human vaccinia-related kinase proteins to toxic metals.

21 January 2018

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NMR solution structure of human vaccinia-related kinase 1 (VRK1) reveals the C-terminal tail essential for its structural stability and autocatalytic activity

21 January 2018

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Spinal muscular atrophy with pontocerebellar hypoplasia is caused by a mutation in the VRK1 gene

21 January 2018

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Shaping genetic alterations in human cancer: the p53 mutation paradigm

21 January 2018

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Mutant p53: one name, many proteins

21 January 2018

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Cytoscape: a software environment for integrated models of biomolecular interaction networks

21 January 2018

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The DNA Damage Response: Making It Safe to Play with Knives

21 January 2018

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Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

21 January 2018

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

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21 January 2018

p53 mutations in cancer

1 reference

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Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion

21 January 2018

1 reference

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Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

21 January 2018

1 reference

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p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

21 January 2018

1 reference

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A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

21 January 2018

1 reference

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Mutant p53: an oncogenic transcription factor

21 January 2018

1 reference

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When mutants gain new powers: news from the mutant p53 field.

21 January 2018

1 reference

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7 January 2021

Tumour suppression by p53: a role for the DNA damage response?

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7 January 2021

The tumor suppressor p53: from structures to drug discovery

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7 January 2021

Posttranslational modification of p53: cooperative integrators of function

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7 January 2021

Mutant p53 gain-of-function in cancer

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7 January 2021

The origins and evolution of the p53 family of genes

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7 January 2021

p63 and p73, the ancestors of p53.

1 reference

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7 January 2021

VRK1 phosphorylates CREB and mediates CCND1 expression

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7 January 2021

10.1016/J.FEBSLET.2014.01.040

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

533055

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

533055

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

533055

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json