(Q24336806)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

title

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

Cyclin dependent kinase inhibitor 1A

29 October 2019

main subject

DNA damage

0 references

1 reference

GOA release 2020-03-11

tumor protein p53

1 reference

cyclin-dependent protein serine/threonine kinase inhibitor activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Aldo Di Leonardo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

author name string

S P Linke

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

K Clarkin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

G M Wahl

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

language of work or name

English

0 references

publication date

1 November 1994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

page(s)

2540-2551

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

Telomeres, telomerase and senescence

29 October 2019

cites work

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Mimosine reversibly arrests cell cycle progression at the G1-S phase border

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Evidence that wild-type TP53, and not genes on either chromosome 1 or 11, controls the tumorigenic phenotype of the human fibrosarcoma HT1080.

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Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

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7 January 2021

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

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7 January 2021

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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7 January 2021

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

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7 January 2021

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

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7 January 2021

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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7 January 2021

Baseline and phosphoramide mustard-induced sister-chromatid exchanges in pharmacists handling anti-cancer drugs

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7 January 2021

DNA topoisomerase II inhibition and gene amplification in V79/B7 cells.

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7 January 2021

Cancer. p53, guardian of the genome

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7 January 2021

Checkpoint policing by p53.

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7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

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7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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7 January 2021

Cell checkpoint and radiosensitivity

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7 January 2021

p21 is a universal inhibitor of cyclin kinases

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7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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7 January 2021

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

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7 January 2021

DNA amplification is rare in normal human cells

1 reference

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7 January 2021

Normal diploid human and rodent cells lack a detectable frequency of gene amplification

1 reference

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7 January 2021

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

1 reference

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7 January 2021

Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase

1 reference

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7 January 2021

Telomere length predicts replicative capacity of human fibroblasts

1 reference

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7 January 2021

Clonal ordering of 17p and 5q allelic losses in Barrett dysplasia and adenocarcinoma

1 reference

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7 January 2021

Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage

1 reference

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7 January 2021

Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes

1 reference

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7 January 2021

Transformation and radiosensitivity of human diploid skin fibroblasts transfected with activated ras oncogene and SV40 T-antigen

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7 January 2021

Transformation and radiosensitivity of human diploid skin fibroblasts transfected with SV40 T-antigen mutants defective in RB and P53 binding domains

1 reference

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7 January 2021

Radiation response of mouse lymphoid and myeloid cell lines. Part I. Sensitivity to killing by ionizing radiation, rate of loss of viability, and cell type of origin

1 reference

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7 January 2021

Radiation response of mouse lymphoid and myeloid cell lines. Part II. Apoptotic death is shown by all lines examined

1 reference

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7 January 2021

Radiation response of mouse lymphoid and myeloid cell lines. Part III. Different signals can lead to apoptosis and may influence sensitivity to killing by DNA double-strand breakage

1 reference

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7 January 2021

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

1 reference

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7 January 2021

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

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7 January 2021

Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins.

1 reference

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7 January 2021

Association of human cyclin E with a periodic G1-S phase protein kinase

1 reference

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7 January 2021

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

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7 January 2021

E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

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7 January 2021

G1 events and regulation of cell proliferation

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7 January 2021

Checkpoints: controls that ensure the order of cell cycle events

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7 January 2021

Oncogenes in radioresistant, noncancerous skin fibroblasts from a cancer-prone family.

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7 January 2021

A cell cycle regulator potentially involved in genesis of many tumor types

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7 January 2021

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

1 reference

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7 January 2021

Delayed chromosomal instability induced by DNA damage

1 reference

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7 January 2021

Complementation by wild-type p53 of interleukin-6 effects on M1 cells: induction of cell cycle exit and cooperativity with c-myc suppression

1 reference

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7 January 2021

Cell cycle analysis of p53-induced cell death in murine erythroleukemia cells

1 reference

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7 January 2021

p53-mediated cell death: relationship to cell cycle control

1 reference

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7 January 2021

The Tumor Suppressor p53 Regulates Its Own Transcription

1 reference

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7 January 2021

Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

1 reference

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7 January 2021

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

1 reference

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7 January 2021

Co-Amplification of rRNA Genes with CAD Genes in N-(Phosphonacetyl)-L-Aspartate-Resistant Syrian Hamster Cells

1 reference

https://api.crossref.org/works/10.1101%2FGAD.8.21.2540

7 January 2021

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

1 reference

https://api.crossref.org/works/10.1101%2FGAD.8.21.2540

7 January 2021

Classification and relationships of induced chromosomal structual changes

1 reference

https://api.crossref.org/works/10.1101%2FGAD.8.21.2540

7 January 2021

Identifiers

DOI

10.1101/GAD.8.21.2540

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7958916%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017