(Q24337413)

1

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Xingzhi Xu

2

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Jia Li

3

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David F Stern

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

7 March 2003

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published in

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volume

278

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page(s)

8468-75

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issue

10

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cites work

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

CHK2 kinase--a busy messenger.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Mutation analysis of the CHK2 gene in breast carcinoma and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Mutation analysis of the CHK2 gene in families with hereditary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Cell cycle regulation of the Saccharomyces cerevisiae polo-like kinase cdc5p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Polo-like kinases: positive regulators of cell division from start to finish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Chk2 activation and phosphorylation-dependent oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

RAD9 and DNA polymerase epsilon form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

gamma-tubulin complexes: binding to the centrosome, regulation and microtubule nucleation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Functional studies on the role of the C-terminal domain of mammalian polo-like kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Tracing the pathway of spindle assembly checkpoint signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

A role for endothelial NO synthase in LTP revealed by adenovirus-mediated inhibition and rescue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

BRCA1 is associated with the centrosome during mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Duplication of ATR inhibits MyoD, induces aneuploidy and eliminates radiation-induced G1 arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Plk1 promotes nuclear translocation of human Cdc25C during prophase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

The polo-like kinase Plx1 prevents premature inactivation of the APC(Fizzy)-dependent pathway in the early Xenopus cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Polo-like kinase-1 is a target of the DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

On the Regulation and Function of Human Polo-like Kinase 1 (PLK1): Effects of Overexpression on Cell Cycle Progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Mutation analysis of the DNA-damage checkpoint gene CHK2 in myelodysplastic syndromes and acute myeloid leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Mutations of the CHK2 gene are found in some osteosarcomas, but are rare in breast, lung, and ovarian tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Analysis of CHK2 in patients with myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Mutations of Chk2 in primary hematopoietic neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

CDC5 and CKII control adaptation to the yeast DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

Chk2 tumour suppressor protein in human spermatogenesis and testicular germ-cell tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200

The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211202200