(Q24529191)

English

Proteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression.

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12 November 2019

Proteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression (English)

1 reference

Europe PubMed Central

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12 November 2019

Cytomegalovirus

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Michael J. Matunis

7

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12 November 2019

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Y Xu

1

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12 November 2019

J H Ahn

2

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12 November 2019

M Cheng

3

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12 November 2019

C M apRhys

4

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12 November 2019

C J Chiou

5

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12 November 2019

J Zong

6

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12 November 2019

G S Hayward

8

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12 November 2019

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1 November 2001

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12 November 2019

Journal of Virology

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12 November 2019

75

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12 November 2019

10683-10695

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12 November 2019

22

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12 November 2019

The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases

1 reference

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24 March 2017

Epstein-barr virus immediate-early protein BZLF1 is SUMO-1 modified and disrupts promyelocytic leukemia bodies

1 reference

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24 March 2017

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

1 reference

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24 March 2017

Role of SUMO-1-modified PML in nuclear body formation

1 reference

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24 March 2017

Sequestration and inhibition of Daxx-mediated transcriptional repression by PML

1 reference

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24 March 2017

SUMO-1 modification activates the transcriptional response of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruption

1 reference

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24 March 2017

CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex

1 reference

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24 March 2017

The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein

1 reference

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24 March 2017

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

1 reference

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24 March 2017

RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor

1 reference

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24 March 2017

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

1 reference

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24 March 2017

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

1 reference

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24 March 2017

Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein

1 reference

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24 March 2017

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

2 references

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24 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

27 September 2017

The transcriptional coactivators p300 and CBP are histone acetyltransferases

1 reference

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24 March 2017

Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins

1 reference

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24 March 2017

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

CREB-binding protein and p300 in transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

RING finger proteins: mediators of ubiquitin ligase activity

1 reference

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24 March 2017

The transcriptional role of PML and the nuclear body

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

Identification of three major sentrinization sites in PML

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

Rb interacts with histone deacetylase to repress transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

Retinoblastoma protein recruits histone deacetylase to repress transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

Temporal Patterns of Human Cytomegalovirus Transcription: Mapping the Viral RNAs Synthesized at Immediate Early, Early, and Late Times After Infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

24 March 2017

SUMO--nonclassical ubiquitin

1 reference

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7 April 2017

Evolution and function of ubiquitin-like protein-conjugation systems

1 reference

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10 May 2017

Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9

1 reference

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27 September 2017

Alphaherpesvirus proteins related to herpes simplex virus type 1 ICP0 affect cellular structures and proteins

1 reference

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27 September 2017

Disruption of PML-associated nuclear bodies by IE1 correlates with efficient early stages of viral gene expression and DNA replication in human cytomegalovirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

27 September 2017

SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.

1 reference

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27 September 2017

Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b

1 reference

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27 September 2017

The human cytomegalovirus IE2 and UL112-113 proteins accumulate in viral DNA replication compartments that initiate from the periphery of promyelocytic leukemia protein-associated nuclear bodies (PODs or ND10)

1 reference

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27 September 2017

Human T-cell leukemia retrovirus-Tax protein is a repressor of nuclear receptor signaling

1 reference

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27 September 2017

Binding of the human cytomegalovirus 80-kDa immediate-early protein (IE2) to minor groove A/T-rich sequences bounded by CG dinucleotides is regulated by protein oligomerization and phosphorylation

1 reference

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27 September 2017

Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PML

1 reference

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27 September 2017

The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

27 September 2017

Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

27 September 2017

Transcriptional repression by the promyelocytic leukemia protein, PML.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

27 September 2017

Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant

1 reference

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27 September 2017

TAF-like functions of human cytomegalovirus immediate-early proteins

1 reference

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27 September 2017

Human cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment

1 reference

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27 September 2017

The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells.

1 reference

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27 September 2017

Construction of adenovirus vectors through Cre-lox recombination

1 reference

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27 September 2017

Evidence that the UL84 gene product of human cytomegalovirus is essential for promoting oriLyt-dependent DNA replication and formation of replication compartments in cotransfection assays

1 reference

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27 September 2017

The IE2 regulatory protein of human cytomegalovirus induces expression of the human transforming growth factor beta1 gene through an Egr-1 binding site

1 reference

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27 September 2017

The 86-kilodalton IE-2 protein of human cytomegalovirus is a sequence-specific DNA-binding protein that interacts directly with the negative autoregulatory response element located near the cap site of the IE-1/2 enhancer-promoter.

1 reference

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27 September 2017

Human cytomegalovirus infection induces transcription and secretion of transforming growth factor beta 1

1 reference

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27 September 2017

Transcriptional activation by the human cytomegalovirus immediate-early proteins: requirements for simple promoter structures and interactions with multiple components of the transcription complex.

1 reference

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27 September 2017

Evaluation of colocalization interactions between the IE110, IE175, and IE63 transactivator proteins of herpes simplex virus within subcellular punctate structures

1 reference

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27 September 2017

CCAAT box-dependent activation of the TATA-less human DNA polymerase alpha promoter by the human cytomegalovirus 72-kilodalton major immediate-early protein

1 reference

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27 September 2017

Human cytomegalovirus IE1 and IE2 proteins block apoptosis

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27 September 2017

Interaction of the 72-kilodalton human cytomegalovirus IE1 gene product with E2F1 coincides with E2F-dependent activation of dihydrofolate reductase transcription

1 reference

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27 September 2017

Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1.

1 reference

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27 September 2017

trans-activation and autoregulation of gene expression by the immediate-early region 2 gene products of human cytomegalovirus

1 reference

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27 September 2017

Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element.

1 reference

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27 September 2017

A human cytomegalovirus early gene has three inducible promoters that are regulated differentially at various times after infection

1 reference

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27 September 2017

The IE2 gene products of human cytomegalovirus specifically down-regulate expression from the major immediate-early promoter through a target sequence located near the cap site

1 reference

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27 September 2017

Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains

1 reference

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27 September 2017

Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins

1 reference

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27 September 2017

A cis-acting element in the major immediate-early (IE) promoter of human cytomegalovirus is required for negative regulation by IE2

1 reference

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27 September 2017

Human cytomegalovirus ie2 negatively regulates alpha gene expression via a short target sequence near the transcription start site

1 reference

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27 September 2017

Effect of PML and PML-RAR on the transactivation properties and subcellular distribution of steroid hormone receptors

1 reference

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27 September 2017

The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition

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30 May 2018

In vivo and in vitro analysis of transcriptional activation mediated by the human cytomegalovirus major immediate-early proteins.

1 reference

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30 May 2018

Differences in cell-type-specific blocks to immediate early gene expression and DNA replication of human, simian and murine cytomegalovirus

1 reference

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30 May 2018

Expression of the acidic nuclear immediate-early protein (IE1) of human cytomegalovirus in stable cell lines and its preferential association with metaphase chromosomes

1 reference

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30 May 2018

Alternative splicing of PML transcripts predicts coexpression of several carboxy-terminally different protein isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

30 May 2018

Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

29 November 2018

Modulation of Fos-mediated AP-1 transcription by the promyelocytic leukemia protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

29 November 2018

Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114650

29 November 2018

Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/11602710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

1 reference

https://pubmed.ncbi.nlm.nih.gov/11602710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SUMO-1 modification of bovine papillomavirus E1 protein is required for intranuclear accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11602710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cycloheximide-enhanced protein in cytomegalovirus-infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11602710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.75.22.10683-10695.2001

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11602710%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

release_mveqio3fsbedxlkih7c6zuqy7i

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11602710%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11602710%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Sitelinks

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