(Q24530588)

English

Recombinant 2-enoyl-CoA hydratase derived from rat peroxisomal multifunctional enzyme 2: role of the hydratase reaction in bile acid synthesis

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scholarly article

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Recombinant 2-enoyl-CoA hydratase derived from rat peroxisomal multifunctional enzyme 2: role of the hydratase reaction in bile acid synthesis (English)

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author name string

Y M Qin

1

author given names

Y M

author last names

Qin

1 reference

19 October 2023

A M Haapalainen

2

author given names

A M

author last names

Haapalainen

1 reference

19 October 2023

D Conry

3

author given names

D

author last names

Conry

1 reference

19 October 2023

D A Cuebas

4

author given names

D A

author last names

Cuebas

1 reference

19 October 2023

J K Hiltunen

5

author given names

J K

author last names

Hiltunen

1 reference

19 October 2023

D K Novikov

6

author given names

D K

author last names

Novikov

1 reference

19 October 2023

language of work or name

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publication date

1 December 1997

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Biochemical Journal

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328 ( Pt 2)

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377-82

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Purification and characterization of an alpha-methylacyl-CoA racemase from human liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

24 March 2017

Crystal structure of enoyl-coenzyme A (CoA) hydratase at 2.5 angstroms resolution: a spiral fold defines the CoA-binding pocket

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

24 March 2017

Peroxisomal multifunctional beta-oxidation protein of Saccharomyces cerevisiae. Molecular analysis of the fox2 gene and gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

24 March 2017

The reactions catalyzed by the inducible bifunctional enzyme of rat liver peroxisomes cannot lead to the formation of bile acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

24 March 2017

Long Chain Enoyl Coenzyme A Hydratase from Pig Heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

24 March 2017

Sterol carrier protein X is peroxisomal 3-oxoacyl coenzyme A thiolase with intrinsic sterol carrier and lipid transfer activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

24 March 2017

Purification and properties of an alpha-methylacyl-CoA racemase from rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

24 March 2017

Substrate specificities of rat liver peroxisomal acyl-CoA oxidases: palmitoyl-CoA oxidase (inducible acyl-CoA oxidase), pristanoyl-CoA oxidase (non-inducible acyl-CoA oxidase), and trihydroxycoprostanoyl-CoA oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

24 March 2017

Peroxisomal βoxidation system of rat liver. Copurification of enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

24 March 2017

Peroxisomal oxidation of the steroid side chain in bile acid formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

27 September 2017

Inhibitors of fatty acid oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

27 September 2017

Peroxisomal bifunctional enzyme deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

27 September 2017

Cloning and sequence determination of cDNA encoding a second rat liver peroxisomal 3-ketoacyl-CoA thiolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

27 September 2017

Presence of three acyl-CoA oxidases in rat liver peroxisomes. An inducible fatty acyl-CoA oxidase, a noninducible fatty acyl-CoA oxidase, and a noninducible trihydroxycoprostanoyl-CoA oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

27 September 2017

Peroxisomal multifunctional enzyme of beta-oxidation metabolizing D-3-hydroxyacyl-CoA esters in rat liver: molecular cloning, expression and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

30 May 2018

Purification and further characterization of peroxisomal trihydroxycoprostanoyl-CoA oxidase from rat liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

30 May 2018

Improved synthesis of 3 alpha, 7 alpha, 12 alpha, 24 = xi-tetrahydroxy-5 beta-cholestan-26-oic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

30 May 2018

Synthesis of four diastereoisomers at carbons 24 and 25 of 3 alpha,7 alpha,12 alpha,24-tetrahydroxy-5 beta-cholestan-26-oic acid, intermediates of bile acid biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

30 May 2018

Stereospecific formation of (24E)-3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholest-24-en-26-oic acid and (24R,25S)-3 alpha,7 alpha,12 alpha,24-tetrahydroxy-5 beta-cholestan-26-oic acid from either (25R)- or (25S)-3 alpha,7 alpha,12 alpha-trihydrox

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

30 May 2018

Separate peroxisomal oxidases for long-chain acyl-CoA and trihydroxycoprostanoyl-CoA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

30 May 2018

Configuration of the 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholest-24-enoic acid, an intermediate in the peroxisomal conversion of 3 alpha,7 alpha,12-trihydroxy-5 beta-cholestanoic acid to cholic acid in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

30 May 2018

Peroxisomal lipid metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218931

29 November 2018

The presence of a new 3-oxoacyl-CoA thiolase in rat liver peroxisomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholest-24-enoic acid as an intermediate in the peroxisomal conversion of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid to cholic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epimerization of 3-hydroxyacyl-CoA esters in rat liver. Involvement of two 2-enoyl-CoA hydratases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-3-hydroxyacyl coenzyme A dehydratase from rat liver peroxisomes. Purification and characterization of a novel enzyme necessary for the epimerization of 3-hydroxyacyl-CoA thioesters

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bile acids. LXXXI. Synthesis and structural assignment of E/Z isomers of substituted methyl hydroxy-5β-cholest-24-en-26-oates

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereochemistry of intermediates in the conversion of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid to cholic acid by rat liver peroxisomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymes converting D-3-hydroxyacyl-CoA to trans-2-enoyl-CoA. Microsomal and peroxisomal isoenzymes in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-stereoselective formation of 3 alpha,7 alpha,12 alpha,24-tetrahydroxy-5 beta-cholestan-26-oic acid during cholic acid biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisomal beta-oxidation. Purification of four novel 3-hydroxyacyl-CoA dehydrogenases from rat liver peroxisomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of historical contingency in the stereochemistry of hydratase-dehydratase enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial beta-oxidation of 2-methyl fatty acids in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changing stereochemistry for a metabolic pathway in vivo. Experiments with the peroxisomal beta-oxidation in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoisomeric inversion of (25R)- and (25S)-3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acids in rat liver peroxisome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of diastereomers of 3 alpha,7 alpha,12 alpha, 24-tetrahydroxy- and 3 alpha,7 alpha,24-trihydroxy-5 beta-cholestan- 26-oic acids and their structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further characterization of the peroxisomal 3-hydroxyacyl-CoA dehydrogenases from rat liver. Relationship between the different dehydrogenases and evidence that fatty acids and the C27 bile acids di- and tri-hydroxycoprostanic acids are metabolized

1 reference

https://pubmed.ncbi.nlm.nih.gov/9371691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3280377

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release_olwk35dpmjentflqkr5yholx24

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