(Q24540429)

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CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15728465%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15728465%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Christopher A. Klebanoff

9

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8 January 2020

Steven Rosenberg

11

object named as

Steven A Rosenberg

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8 January 2020

author name string

Paul A Antony

1

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8 January 2020

Ciriaco A Piccirillo

2

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8 January 2020

Akgül Akpinarli

3

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8 January 2020

Steven E Finkelstein

4

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8 January 2020

Paul J Speiss

5

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8 January 2020

Deborah R Surman

6

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8 January 2020

Douglas C Palmer

7

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8 January 2020

Chi-Chao Chan

8

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8 January 2020

Willem W Overwijk

10

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8 January 2020

Nicholas P Restifo

12

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8 January 2020

language of work or name

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publication date

1 March 2005

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8 January 2020

Journal of Immunology

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8 January 2020

174

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8 January 2020

2591-2601

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8 January 2020

5

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8 January 2020

IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

24 March 2017

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

24 March 2017

T cell homeostatic proliferation elicits effective antitumor autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

24 March 2017

Tumor-specific CD4+ T cells have a major "post-licensing" role in CTL mediated anti-tumor immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

24 March 2017

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

7 April 2017

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

7 April 2017

Tolerance, not immunity, crucially depends on IL-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Interleukin-2 is essential for CD4+CD25+ regulatory T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Helping the CD8(+) T-cell response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Shedding light on immunotherapy for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

IL-2, regulatory T cells, and tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

IL-21 induces tumor rejection by specific CTL and IFN-gamma-dependent CXC chemokines in syngeneic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Natural versus adaptive regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Adoptive therapy with CD8(+) T cells: it may get by with a little help from its friends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Interleukin 2 signaling is required for CD4(+) regulatory T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

CD4+ CD25+ suppressor T cells: more questions than answers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Do CD4+ CD25+ immunoregulatory T cells hinder tumor immunotherapy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Interleukin-2 fusion toxin: targeted therapy for cutaneous T cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Autoimmunity and the immunotherapy of cancer: targeting the "self" to destroy the "other".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Progress in human tumour immunology and immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Cloning, expression and tissue distribution of the murine homologue of the melanocyte lineage-specific antigen gp100.

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

https://api.crossref.org/works/10.4049%2FJIMMUNOL.174.5.2591

7 January 2021

based on heuristic

inferred from DOI database lookup

CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Interleukin-2 deficient mice: a new model to study autoimmunity and self-tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

T-cell-mediated suppression of anti-tumor immunity. An explanation for progressive growth of an immunogenic tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

27 September 2017

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

30 May 2018

Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

30 May 2018

CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

30 May 2018

Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

29 November 2018

CD8 lethargy in the absence of CD4 help.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

29 November 2018

CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403291

29 November 2018

CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eradication of established tumors by CD8+ T cell adoptive immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The risk of autoimmunity associated with tumor immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting Edge: Precursor Frequency Affects the Helper Dependence of Cytotoxic T Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Origin of regulatory T cells with known specificity for antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential Role for STAT5 Signaling in CD25+CD4+ Regulatory T Cell Homeostasis and the Maintenance of Self-Tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Priming of naive T cells inside tumors leads to eradication of established tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune responses in interleukin-2-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15728465

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.174.5.2591

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15728465%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15728465%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15728465%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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