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Interleukin-24 and its receptors
scientific article
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instance of
scholarly article
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title
Interleukin-24 and its receptors
(English)
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main subject
interleukins
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author name string
Mai Wang
series ordinal
1
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Peng Liang
series ordinal
2
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language of work or name
English
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publication date
February 2005
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published in
Immunology
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volume
114
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page(s)
166-70
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issue
2
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cites work
Interleukin-10 and the interleukin-10 receptor
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Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)
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Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R
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Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2
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mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic
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Cutting edge: FISP (IL-4-induced secreted protein), a novel cytokine-like molecule secreted by Th2 cells
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IL-24 is expressed by rat and human macrophages
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Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types
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Interleukin 20: discovery, receptor identification, and role in epidermal function
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Identification of a novel ligand-receptor pair constitutively activated by ras oncogenes
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Cutaneous rat wounds express c49a, a novel gene with homology to the human melanoma differentiation associated gene, mda-7
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Melanoma differentiation-associated gene-7/IL-24 gene enhances NF-kappa B activation and suppresses apoptosis induced by TNF.
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Loss of novel mda-7 splice variant (mda-7s) expression is associated with metastatic melanoma.
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Conservation of the genomic structure and receptor-mediated signaling between human and rat IL-24.
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MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.
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Expression patterns of IL-10 ligand and receptor gene families provide leads for biological characterization.
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The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells
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The Class II cytokine receptor (CRF2) family: overview and patterns of receptor-ligand interactions
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Class II cytokine receptors and their ligands: key antiviral and inflammatory modulators
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28 September 2017
INGN-241. Introgen
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28 September 2017
MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine
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28 September 2017
mda-7 (IL-24): signaling and functional roles.
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Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions
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The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24.
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Cutting edge: immune cells as sources and targets of the IL-10 family members?
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Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2.
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28 September 2017
Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes
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28 September 2017
Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
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28 September 2017
Mda-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy
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28 September 2017
Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9.
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PubMed Central
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28 September 2017
Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
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28 September 2017
Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor.
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30 May 2018
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties
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21 January 2018
Epidermal overexpression of interleukin-19 and -20 mRNA in psoriatic skin disappears after short-term treatment with cyclosporine a or calcipotriol.
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21 January 2018
Mda-7/IL-24 induces apoptosis of diverse cancer cell lines through JAK/STAT-independent pathways
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21 January 2018
Tumor suppressor MDA-7/IL-24 selectively inhibits vascular smooth muscle cell growth and migration.
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Identifiers
DOI
10.1111/J.1365-2567.2005.02094.X
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PMCID
1782067
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PubMed ID
15667561
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ResearchGate publication ID
8063292
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