(Q24791546)

English

Site-specific incorporation of N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified 'ultra-mild' DNA synthesis

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scholarly article

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Site-specific incorporation of N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified 'ultra-mild' DNA synthesis (English)

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author name string

Ludovic C J Gillet

1

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Jawad Alzeer

2

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Orlando D Schärer

3

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language of work or name

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publication date

2005

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Nucleic Acids Research

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33

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1961-9

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6

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The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

7 April 2017

Translesion synthesis of acetylaminofluorene-dG adducts by DNA polymerase zeta is stimulated by yeast Rev1 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Synthesis of the C8-deoxyguanosine adduct of the food mutagen IQ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Damage recognition in nucleotide excision repair of DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Nucleotide excision repair: from E. coli to man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Molecular mechanism of nucleotide excision repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Mechanism of open complex and dual incision formation by human nucleotide excision repair factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Bipartite substrate discrimination by human nucleotide excision repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

The sensitivity of human fibroblasts to N-acetoxy-2-acetylaminofluorene is determined by the extent of transcription-coupled repair, and/or their capability to counteract RNA synthesis inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Double strand breaks in DNA inhibit nucleotide excision repair in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Recognition of DNA adducts by human nucleotide excision repair. Evidence for a thermodynamic probing mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Mutagenic replication in human cell extracts of DNA containing site-specific N-2-acetylaminofluorene adducts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Synthetic and oxidative studies on 8-(arylamino)-2'-deoxyguanosine and -guanosine derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Human and E.coli excinucleases are affected differently by the sequence context of acetylaminofluorene-guanine adduct

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Site-specific modification of the lactose operator with acetylaminofluorene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Targeted mutations induced by a single acetylaminofluorene DNA adduct in mammalian cells and bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

2-Nitrofluorene and related compounds: prevalence and biological effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Single adduct mutagenesis: strong effect of the position of a single acetylaminofluorene adduct within a mutation hot spot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Acetylaminofluorene bound to different guanines of the sequence -GGCGCC- is excised with different efficiencies by the UvrABC excision nuclease in a pattern not correlated to the potency of mutation induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Polymorphism in N-2-acetylaminofluorene induced DNA structure as revealed by DNase I footprinting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Carcinogen-induced frameshift mutagenesis in repetitive sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 September 2017

Arylamidation and arylation by the carcinogen N-2-fluorenylacetamide: a sensitive and rapid radiochemical assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

30 May 2018

Site-specific DNA substrates for human excision repair: comparison between deoxyribose and base adducts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

30 May 2018

Quantification of adducts formed in DNA treated with N-acetoxy-2-acetylaminofluorene or N-hydroxy-2-aminofluorene: comparison of trifluoroacetic acid and enzymatic degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

30 May 2018

8-(N-2-Fluorenylacetamido) guanosine, an Arylamidation Reaction Product of Guanosine and the Carcinogen N-Acetoxy-N-2-fluorenylacetamide in Neutral Solution*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

30 May 2018

Mutagenesis by single site-specific arylamine-DNA adducts. Induction of mutations at multiple sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

30 May 2018

Localization of DNA repair synthesis by human cell extracts to a short region at the site of a lesion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

30 May 2018

Induction of mutations by N-acetoxy-N-acetyl-2-aminofluorene modified M13 viral DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

30 May 2018

Isolation and characterization of oligodeoxynucleotides containing dG-N2-AAF and oxidation products of dG-C8-AF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

30 May 2018

On the mechanism of frameshift (deletion) mutagenesis in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

30 May 2018

Site-specific synthesis and properties of oligonucleotides containing C8-deoxyguanosine adducts of the dietary mutagen IQ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 November 2018

Mutagenic events in Escherichia coli and mammalian cells generated in response to acetylaminofluorene-derived DNA adducts positioned in the Nar I restriction enzyme site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 November 2018

Observation and elimination of N-acetylation of oligonucleotides prepared using fast-deprotecting phosphoramidites and ultra-mild deprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 November 2018

Influence of flanking sequence context on the mutagenicity of acetylaminofluorene-derived DNA adducts in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 November 2018

Determination of minimum substrate size for human excinuclease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1074722

28 November 2018

Structural characterization of an N-acetyl-2-aminofluorene (AAF) modified DNA oligomer by NMR, energy minimization, and molecular dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solid-phase synthesis of oligonucleotides containing site-specific N-(2'-deoxyguanosin-8-yl)-2-(acetylamino)fluorene adducts using 9-fluorenylmethoxycarbonyl as the base-protecting group

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-2-aminofluorene and N-2 acetylaminofluorene adducts: the local sequence context of an adduct and its chemical structure determine its replication properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of transcription-coupled repair of acetylaminofluorene DNA adducts in human fibroblasts contrasts their efficient inhibition of transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenic specificity of (acetylamino)fluorene-derived DNA adducts in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assay for nucleotide excision repair protein activity using fractionated cell extracts and UV-damaged plasmid DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual-incision assays for nucleotide excision repair using DNA with a lesion at a specific site

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation of C8-amine and acetylamine adducts of 2'-deoxyguanosine suitably protected for DNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent binding of a new reaction product of the carcinogen N-hydroxy-N-2-acetylaminofluorene with guanine in rat liver DNA in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synthesis of oligoribonucleotides. Part XI. Preparation of ribonucleoside 2'-acetal 3'-esters by selective deacylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation and characterization of a viral DNA molecule containing a site-specific 2-aminofluorene adduct: a new probe for mutagenesis by carcinogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction of plasmids containing a unique acetylaminofluorene adduct located within a mutation hot spot. A new probe for frameshift mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition and repair of 2-aminofluorene- and 2-(acetylamino)fluorene-DNA adducts by UVRABC nuclease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strong sequence-dependent polymorphism in adduct-induced DNA structure: analysis of single N-2-acetylaminofluorene residues bound within the NarI mutation hot spot

1 reference

https://pubmed.ncbi.nlm.nih.gov/15814813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GKI335

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