(Q24810481)

21 June 2017

Cheaper faster drug development validated by the repositioning of drugs against neglected tropical diseases. (English)

1 reference

neglected tropical disease

21 June 2017

0 references

0 references

biomedical engineering

0 references

0 references

tnp-470

1 reference

ChEBI release 2020-05-28

12

1 reference

21 June 2017

6

Larisa N Soldatova

1 reference

21 June 2017

Elizabeth Bilsland

2

0 references

author name string

Kevin Williams

1

1 reference

21 June 2017

Andrew Sparkes

3

1 reference

21 June 2017

Wayne Aubrey

4

1 reference

21 June 2017

Michael Young

5

1 reference

21 June 2017

Kurt De Grave

7

1 reference

21 June 2017

Jan Ramon

8

1 reference

21 June 2017

Michaela de Clare

9

1 reference

21 June 2017

Worachart Sirawaraporn

10

1 reference

21 June 2017

Stephen G Oliver

11

1 reference

21 June 2017

language of work or name

English

0 references

publication date

1 March 2015

1 reference

Journal of the Royal Society Interface

21 June 2017

1 reference

21 June 2017

12

1 reference

21 June 2017

20141289

1 reference

21 June 2017

104

1 reference

Open Babel: An open chemical toolbox

21 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Towards Robot Scientists for autonomous scientific discovery.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

The automation of science.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Functional expression of parasite drug targets and their human orthologs in yeast

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Virtual screening: an endless staircase?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Functional genomic hypothesis generation and experimentation by a robot scientist

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Automated design of ligands to polypharmacological profiles.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Large-scale prediction and testing of drug activity on side-effect targets.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Drugs for Neglected Diseases initiative model of drug development for neglected diseases: current status and future challenges.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

The productivity crisis in pharmaceutical R&D.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

A survey of yeast genomic assays for drug and target discovery.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Emergence of orphan drugs in the United States: a quantitative assessment of the first 25 years.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Antiparasitic activities of novel, orally available fumagillin analogs.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

28 September 2017

New uses for old drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

An autonomous molecular computer for logical control of gene expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Angiogenesis inhibitors specific for methionine aminopeptidase 2 as drugs for malaria and leishmaniasis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Infectious diseases. Drug developers finally take aim at a neglected disease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

Molecular characterization of dihydrofolate reductase in relation to antifolate resistance in Plasmodium vivax.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345494

28 November 2018

Identifiers

DOI

10.1098/RSIF.2014.1289

1 reference

OpenCitations bibliographic resource ID

21 June 2017

3688945

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference