(Q24811550)

5 July 2017

Interlaboratory evaluation of rat hepatic gene expression changes induced by methapyrilene (English)

1 reference

5 July 2017

Jeffrey F Waring

1

1 reference

5 July 2017

Roger G Ulrich

2

1 reference

5 July 2017

Nick Flint

3

1 reference

5 July 2017

David Morfitt

4

1 reference

5 July 2017

Arno Kalkuhl

5

1 reference

5 July 2017

Frank Staedtler

6

1 reference

5 July 2017

Michael Lawton

7

1 reference

5 July 2017

Johanna M Beekman

8

1 reference

5 July 2017

Laura Suter

9

1 reference

5 July 2017

language of work or name

English

0 references

publication date

1 March 2004

1 reference

Environmental Health Perspectives

5 July 2017

1 reference

5 July 2017

112

1 reference

5 July 2017

439-448

1 reference

5 July 2017

4

1 reference

Cluster analysis and display of genome-wide expression patterns

5 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Expression monitoring by hybridization to high-density oligonucleotide arrays

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Liver tumors induced in rats by oral administration of the antihistaminic methapyrilene hydrochloride

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Cloning of rat 17 beta-hydroxysteroid dehydrogenase type 2 and characterization of tissue distribution and catalytic activity of rat type 1 and type 2 enzymes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

The gene encoding rat insulinlike growth factor-binding protein 1 is rapidly and highly induced in regenerating liver

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Block principal component analysis with application to gene microarray data classification

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Oxygen deprivation induced cell death: an update

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

The promise of toxicogenomics.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Transcriptional activation of heme oxygenase-1 and its functional significance in acetaminophen-induced hepatitis and hepatocellular injury in the rat.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Importance of replication in microarray gene expression studies: statistical methods and evidence from repetitive cDNA hybridizations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Cell cycle controls: potential targets for chemical carcinogens?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Effects of induction and inhibition of cytochromes P450 on the hepatotoxicity of methapyrilene

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Examination of genotoxicity, toxicity and morphologic alterations in hepatocytes following in vivo or in vitro exposure to methapyrilene

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

DNA methylation and oncogene expression in methapyrilene-induced rat liver tumors and in treated hepatocytes in culture.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Insulin-like growth factor binding protein-1 over-expression in transgenic mice inhibits hepatic preneoplasia

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Induction of GADD45 and GADD153 in neuroblastoma cells by dopamine-induced toxicity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Identifying toxic mechanisms using DNA microarrays: evidence that an experimental inhibitor of cell adhesion molecule expression signals through the aryl hydrocarbon nuclear receptor

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Protein expression analysis of drug-mediated hepatotoxicity in the Sprague-Dawley rat.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Expression profiling of acetaminophen liver toxicity in mice using microarray technology

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Carcinogenesis by nonmutagenic chemicals: early response of rat liver cells induced by methapyrilene.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1241897

Methapyrilene hepatotoxicity is associated with increased hepatic glutathione, the formation of glucuronide conjugates, and enterohepatic recirculation

28 November 2018

1 reference

12 December 2020

Identification of toxicologically predictive gene sets using cDNA microarrays

1 reference

12 December 2020

A study of the potential genotoxicity of methapyrilene and related antihistamines using the hepatocyte/DNA repair assay

1 reference

12 December 2020

Effects of methapyrilene on rat hepatic xenobiotic metabolizing enzymes and liver morphology

1 reference

12 December 2020

The hepatocarcinogen methapyrilene but not the analog pyrilamine induces sustained hepatocellular replication and protein alterations in F344 rats in a 13-week feed study

1 reference

12 December 2020

Methapyrilene hepatotoxicity is associated with oxidative stress, mitochondrial disfunction and is prevented by the Ca2+ channel blocker verapamil

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.6643

1 reference

5 July 2017

1 reference

5 July 2017

1 reference