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How does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)?
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Europe PubMed Central
PMCID
4772697
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
title
How does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)?
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4772697
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
main subject
Human T-lymphotropic virus 1
0 references
leukemia
1 reference
based on heuristic
inferred from title
author
Charles Bangham
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4772697
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
author name string
Lee Ratner
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4772697
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
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25 February 2020
language of work or name
English
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publication date
27 September 2015
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Europe PubMed Central
PMCID
4772697
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
published in
Current opinion in virology
2 references
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PubMed
stated in
Europe PubMed Central
PMCID
4772697
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
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25 February 2020
volume
14
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Europe PubMed Central
PMCID
4772697
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
page(s)
93-100
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Europe PubMed Central
PMCID
4772697
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
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HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation
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A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation
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The neutralizing function of the anti-HTLV-1 antibody is essential in preventing in vivo transmission of HTLV-1 to human T cells in NOD-SCID/γcnull (NOG) mice
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28 September 2017
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The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma
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Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission
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HTLV-1 clonality in adult T-cell leukaemia and non-malignant HTLV-1 infection
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28 September 2017
HTLV-1 bZIP factor induces inflammation through labile Foxp3 expression
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Human T-cell leukemia virus type 1: replication, proliferation and propagation by Tax and HTLV-1 bZIP factor
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Strongyloidiasis and infective dermatitis alter human T lymphotropic virus-1 clonality in vivo
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Genome-wide determinants of proviral targeting, clonal abundance and expression in natural HTLV-1 infection
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HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells
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28 September 2017
HTLV-1-infected T cells contain a single integrated provirus in natural infection
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28 September 2017
HTLV-I tax increases genetic instability by inducing DNA double strand breaks during DNA replication and switching repair to NHEJ.
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28 September 2017
Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy
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28 September 2017
KIR2DL2 enhances protective and detrimental HLA class I-mediated immunity in chronic viral infection
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28 September 2017
HTLV-1 and innate immunity
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28 September 2017
Molecular determinants of human T-lymphotropic virus type 1 transmission and spread
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28 September 2017
Molecular aspects of HTLV-1 entry: functional domains of the HTLV-1 surface subunit (SU) and their relationships to the entry receptors
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28 September 2017
HTLV-1 propels thymic human T cell development in "human immune system" Rag2⁻/⁻ gamma c⁻/⁻ mice
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28 September 2017
Adult T cell leukemia/lymphoma: FoxP3(+) cells and the cell-mediated immune response to HTLV-1.
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28 September 2017
NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ.
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28 September 2017
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo
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28 September 2017
The host genomic environment of the provirus determines the abundance of HTLV-1-infected T-cell clones
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28 September 2017
Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia
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28 September 2017
Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy
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28 September 2017
Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission
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28 September 2017
HLA class I binding of HBZ determines outcome in HTLV-1 infection
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28 September 2017
Activator-dependent p300 acetylation of chromatin in vitro: enhancement of transcription by disruption of repressive nucleosome-nucleosome interactions
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28 September 2017
Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbits
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28 September 2017
Human T-lymphotropic virus type 1-induced CC chemokine ligand 22 maintains a high frequency of functional FoxP3+ regulatory T cells.
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28 September 2017
The HBZ gene, a key player in HTLV-1 pathogenesis
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28 September 2017
CTL quality and the control of human retroviral infections
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28 September 2017
Stromal cell-mediated suppression of human T-cell leukemia virus type 1 expression in vitro and in vivo by type I interferon
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28 September 2017
Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-kappaB.
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28 September 2017
HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase
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28 September 2017
Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation
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28 September 2017
High frequency of CD4+FoxP3+ cells in HTLV-1 infection: inverse correlation with HTLV-1-specific CTL response
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28 September 2017
In vivo T lymphocyte dynamics in humans and the impact of human T-lymphotropic virus 1 infection
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Pathological features of diseases associated with human T-cell leukemia virus type I.
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28 September 2017
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation
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28 September 2017
HBZ, a new important player in the mystery of adult T-cell leukemia
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28 September 2017
HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells
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28 September 2017
Cellular immune response to HTLV-1.
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28 September 2017
Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I-associated neuroimmunological disease
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28 September 2017
Low frequency of CD94/NKG2A+ T lymphocytes in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis, but not in asymptomatic carriers
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28 September 2017
Immunopathogenesis of human T cell lymphotropic virus type I-associated neurologic disease
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28 September 2017
High frequencies of Th1-type CD4(+) T cells specific to HTLV-1 Env and Tax proteins in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis
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PubMed Central
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28 September 2017
High production of interferon gamma but not interleukin-2 by human T-lymphotropic virus type I-infected peripheral blood mononuclear cells
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28 September 2017
The influence of HLA class I alleles and heterozygosity on the outcome of human T cell lymphotropic virus type I infection
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28 September 2017
Suppression of DNA repair by human T cell leukemia virus type 1 Tax is rescued by a functional p53 signaling pathway
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28 September 2017
HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
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28 September 2017
Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
28 September 2017
Clonal expansion of human T-cell leukemia virus type I-infected cells in asymptomatic and symptomatic carriers without malignancy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
28 September 2017
Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
28 September 2017
Circulating CD8+ cytotoxic T lymphocytes specific for HTLV-I pX in patients with HTLV-I associated neurological disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
28 September 2017
Natural killer (NK) cells in HTLV-I-associated myelopathy/tropical spastic paraparesis-decrease in NK cell subset populations and activity in HTLV-I seropositive individuals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
28 September 2017
Cellular immune surveillance against HTLV-I infected T lymphocytes in HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
28 September 2017
An animal model of adult T-cell leukemia: humanized mice with HTLV-1-specific immunity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
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31 May 2018
A transgenic mouse model of human T cell leukemia virus type 1-associated diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
31 May 2018
HBZ and its roles in HTLV-1 oncogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
31 May 2018
HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
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31 May 2018
Meta-Analysis on the Use of Zidovudine and Interferon-Alfa in Adult T-Cell Leukemia/Lymphoma Showing Improved Survival in the Leukemic Subtypes
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
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28 November 2018
FoxP3+ regulatory T cells are distinct from leukemia cells in HTLV-1-associated adult T-cell leukemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
28 November 2018
Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
28 November 2018
Integration patterns of HTLV-I provirus in relation to the clinical course of ATL: frequent clonal change at crisis from indolent disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772697
retrieved
28 November 2018
Interaction of HTLV-1 Tax with minichromosome maintenance proteins accelerates the replication timing program
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/26414684
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.COVIRO.2015.09.004
1 reference
stated in
Europe PubMed Central
PMCID
4772697
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
PMCID
4772697
1 reference
stated in
Europe PubMed Central
PMCID
4772697
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
PubMed ID
26414684
1 reference
stated in
Europe PubMed Central
PMCID
4772697
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414684%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
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