(Q26828548)

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Redox status in mammalian cells and stem cells during culture in vitro: critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance

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scholarly article

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12 October 2019

4 November 2019

19 November 2019

28 November 2019

11 December 2019

15 December 2019

22 December 2019

29 April 2021

Redox status in mammalian cells and stem cells during culture in vitro: critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance (English)

1 reference

1 reference

12 October 2019

inorganic compound

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4 November 2019

1 reference

19 November 2019

transport protein

1 reference

28 November 2019

DNA-binding protein

1 reference

11 December 2019

membrane protein

1 reference

15 December 2019

transcription factor

1 reference

22 December 2019

nuclear factor erythroid 2-related factor 2

1 reference

29 April 2021

author name string

Tetsuro Ishii

1

1 reference

Giovanni E. Mann

2

1 reference

language of work or name

1 reference

publication date

2014

1 reference

18 April 2014

8 references

12 October 2019

4 November 2019

19 November 2019

28 November 2019

11 December 2019

15 December 2019

22 December 2019

29 April 2021

9 references

12 October 2019

4 November 2019

19 November 2019

28 November 2019

11 December 2019

15 December 2019

22 December 2019

29 April 2021

2

1 reference

786-94

1 reference

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

8 references

Europe PubMed Central

12 October 2019

Europe PubMed Central

4 November 2019

Europe PubMed Central

19 November 2019

Europe PubMed Central

28 November 2019

Europe PubMed Central

11 December 2019

Europe PubMed Central

15 December 2019

Europe PubMed Central

22 December 2019

Europe PubMed Central

29 April 2021

Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

7 April 2017

NF-E2–Related Factor 2 Promotes Atherosclerosis by Effects on Plasma Lipoproteins and Cholesterol Transport That Overshadow Antioxidant Protection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

7 April 2017

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

7 April 2017

Activation transcription factor-4 induced by fibroblast growth factor-2 regulates vascular endothelial growth factor-A transcription in vascular smooth muscle cells and mediates intimal thickening in rat arteries following balloon injury

1 reference

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FSH and bFGF stimulate the production of glutathione in cultured rat Sertoli cells

1 reference

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7 April 2017

Atherosclerosis. the road ahead

1 reference

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7 April 2017

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

1 reference

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Mesenchymal stem cells as a feeder layer can prevent apoptosis of expanded hematopoietic stem cells derived from cord blood

1 reference

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1 reference

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The role of basic fibroblast growth factor in glioblastoma multiforme and glioblastoma stem cells and in their in vitro culture

1 reference

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28 September 2017

Fibroblast growth factor-2 signaling in neurogenesis and neurodegeneration.

1 reference

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Effects of 4-hydroxynonenal on vascular endothelial and smooth muscle cell redox signaling and function in health and disease

1 reference

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28 September 2017

Sequestosome1/p62: a regulator of redox-sensitive voltage-activated potassium channels, arterial remodeling, inflammation, and neurite outgrowth

1 reference

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28 September 2017

Janus-like role of fibroblast growth factor 2 in arteriosclerotic coronary artery disease: atherogenesis and angiogenesis

1 reference

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28 September 2017

Stem cell bioengineering strategies to widen the therapeutic applications of haematopoietic stem/progenitor cells from umbilical cord blood.

1 reference

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28 September 2017

The SLC3 and SLC7 families of amino acid transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Substrates and supplements for hESCs: a critical review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Chemically defined conditions for human iPSC derivation and culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Good manufacturing practice and clinical-grade human embryonic stem cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Signal integration and diversification through the p62 scaffold protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Redox imbalance in cystine/glutamate transporter-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Fate of 4-hydroxynonenal in vivo: disposition and metabolic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Induction of glutathione synthesis in macrophages by oxidized low-density lipoproteins is mediated by consensus antioxidant response elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

The macrophage foam cell as a target for therapeutic intervention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: involvement of the glutathione system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Transport of cystine and cysteine in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Induction of cystine and glutamate transport activity in human fibroblasts by diethyl maleate and other electrophilic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Promotion of replication in lymphoid cells by specific thiols and disulfides in vitro. Effects on mouse lymphoma cells in comparison with splenic lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Role of membrane transport in metabolism and function of glutathione in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 September 2017

Distinguishing amino acid transport systems of a given cell or tissue

1 reference

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1 reference

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Differentiation of functionally active mouse T lymphocytes from functionally inactive bone marrow precursors. III. Induction of T-cell activities by growth of bone marrow on feeder layers prepared from mouse thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

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Fibroblast growth factor 2 positively regulates expression of activating transcription factor 4 in osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

31 May 2018

Transcriptional control of cystine/glutamate transporter gene by amino acid deprivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

31 May 2018

Adaptive enhancement of cystine and glutamate uptake in human diploid fibroblasts in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

31 May 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

31 May 2018

Induction of cystine transport activity in mouse peritoneal macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

31 May 2018

Mouse lymphoma L1210 cells acquire a new cystine transport activity upon adaptation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

31 May 2018

Induction of cystine transport activity in human fibroblasts by oxygen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

31 May 2018

FGF-2 induces neuronal death through upregulation of system xc-.

1 reference

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28 November 2018

Burn injury induces the expression of cystine/glutamate transporter (x(c)(-)) in mouse T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 November 2018

Gamma-tocopheryl quinone, not alpha-tocopheryl quinone, induces adaptive response through up-regulation of cellular glutathione and cysteine availability via activation of ATF4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 November 2018

Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal.

1 reference

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28 November 2018

Distribution of cystine/glutamate exchange transporter, system x(c)-, in the mouse brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085355

28 November 2018

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1 reference

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1 reference

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Formation of sulfhydryl groups in the culture medium by human diploid fibroblasts

1 reference

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28 November 2018

Regulation of glutathione levels in mouse spleen lymphocytes by transport of cysteine

1 reference

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12 December 2020

based on heuristic

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Mechanism of growth promotion of mouse lymphoma L1210 cells in vitro by feeder layer or 2-mercaptoethanol

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exchange of cystine and glutamate across plasma membrane of human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synergistic action of the copper chelator bathocuproine sulphonate and cysteine in enhancing growth of L1210 cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of the clonal growth and differentiation of feeder layer dependent mouse embryonal carcinoma cells by beta-mercaptoethanol

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of antioxidants on cultured human diploid fibroblasts exposed to cystine-free medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in cystine transport activity and glutathione level in mouse peritoneal macrophages exposed to oxidized low-density lipoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of macrophage (Mphi) scavenger receptor, CD36, in cultured human aortic smooth muscle cells in association with expression of peroxisome proliferator activated receptor-gamma, which regulates gain of Mphi-like phenotype in vitro, and its

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of growth stimulation of L1210 cells by 2-mercaptoethanol in vitro. Role of the mixed disulfide of 2-mercaptoethanol and cysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of proliferation of haemopoietic stem cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutral amino acid transport in mouse peritoneal macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel function of glutamine in cell culture: utilization of glutamine for the uptake of cystine in human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/25009780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.REDOX.2014.04.008

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