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Immune Checkpoint Blockade in Cancer Therapy
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PubMed
review article
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Europe PubMed Central
title
Immune Checkpoint Blockade in Cancer Therapy
(English)
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stated in
PubMed
author name string
M. A. Postow
series ordinal
1
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Crossref
M. K. Callahan
series ordinal
2
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Crossref
J. D. Wolchok
series ordinal
3
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
10 June 2015
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stated in
PubMed
published in
Journal of Clinical Oncology
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PubMed
volume
33
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PubMed
page(s)
1974-82
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PubMed
issue
17
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PubMed
cites work
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
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Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4
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Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
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Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors
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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
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Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
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Genetic basis for clinical response to CTLA-4 blockade in melanoma
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Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma
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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
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PubMed Central
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Biomarkers on melanoma patient T cells associated with ipilimumab treatment
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28 September 2017
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28 September 2017
Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study.
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28 September 2017
CTLA-4 blockade with ipilimumab: long-term follow-up of 177 patients with metastatic melanoma
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28 September 2017
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma.
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28 September 2017
Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
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PubMed Central
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28 September 2017
Immune parameters affecting the efficacy of chemotherapeutic regimens
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PubMed Central
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28 September 2017
Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial
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28 September 2017
Anti-CTLA-4 antibody therapy associated autoimmune hypophysitis: serious immune related adverse events across a spectrum of cancer subtypes
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28 September 2017
Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
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28 September 2017
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
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28 September 2017
The heterogeneity of the kinetics of response to ipilimumab in metastatic melanoma: patient cases
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28 September 2017
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
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28 September 2017
Tissue expression of PD-L1 mediates peripheral T cell tolerance.
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28 September 2017
Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer
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PubMed Central
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28 September 2017
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp
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28 September 2017
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
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PubMed Central
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28 September 2017
CTLA-4 is a second receptor for the B cell activation antigen B7
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28 September 2017
Ipilimumab in patients with melanoma and autoimmune disease
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31 May 2018
Opportunistic infections in patients treated with immunotherapy for cancer
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31 May 2018
Increased frequency of ICOS+ CD4 T cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy
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PubMed Central
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31 May 2018
An abscopal response to radiation and ipilimumab in a patient with metastatic non-small cell lung cancer.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
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31 May 2018
Imaging of CTLA4 blockade-induced cell replication with (18)F-FLT PET in patients with advanced melanoma treated with tremelimumab
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PubMed Central
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31 May 2018
Randomized phase III trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non--small-cell lung cancer: a Southwest Oncology Group trial
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31 May 2018
Immunological and biological changes during ipilimumab treatment and their potential correlation with clinical response and survival in patients with advanced melanoma
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28 November 2018
Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma
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28 November 2018
Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trial
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28 November 2018
Case records of the Massachusetts General Hospital. Case 21-2013. A 68-year-old man with metastatic melanoma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Ipilimumab-induced acute severe colitis treated by infliximab.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Efficacy and safety of retreatment with ipilimumab in patients with pretreated advanced melanoma who progressed after initially achieving disease control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab: detailed safety analysis from a phase 3 trial in patients with advanced melanoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
An immune-active tumor microenvironment favors clinical response to ipilimumab
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Anti-CTLA-4 antibody-induced Guillain-Barré syndrome in a melanoma patient
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Phase 1 dose-escalation trial of tremelimumab plus sunitinib in patients with metastatic renal cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Infliximab in the treatment of anti-CTLA4 antibody (ipilimumab) induced immune-related colitis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Neutropenia in a patient treated with ipilimumab (anti-CTLA-4 antibody).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Therapeutic efficacy of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with metastatic melanoma unresponsive to prior systemic treatments: clinical and immunological evidence from three patient cases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Immune-mediated red cell aplasia after anti-CTLA-4 immunotherapy for metastatic melanoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
retrieved
28 November 2018
Cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma: a new cause of uveitis
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980573
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28 November 2018
New monoclonal antibodies against B-cell antigens: Possible new strategies for diagnosis of primary cutaneous B-cell lymphomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25605845
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Severe relapse in a multiple sclerosis patient associated with ipilimumab treatment of melanoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25605845
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Successful treatment with Ipilimumab and Interleukin-2 in two patients with metastatic melanoma and systemic autoimmune disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25605845
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Experience in daily practice with ipilimumab for the treatment of patients with metastatic melanoma: an early increase in lymphocyte and eosinophil counts is associated with improved survival
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25605845
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1200/JCO.2014.59.4358
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
668982
OpenCitations bibliographic resource ID
668982
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
668982
PMCID
4980573
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
668982
PubMed ID
25605845
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
668982
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