(Q26991715)

PubMed

issue

8

1 reference

PubMed

page(s)

1356-65

1 reference

Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites

PubMed

cites work

1 reference

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Kynurenine pathway inhibition as a therapeutic strategy for neuroprotection

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Kynurenine is an endothelium-derived relaxing factor produced during inflammation

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Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid

21 January 2018

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Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid

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Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain

21 January 2018

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Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS

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Endogenous neurotoxins from tryptophan

21 January 2018

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Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease

21 January 2018

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Indoleamine 2,3 dioxygenase and quinolinic acid immunoreactivity in Alzheimer's disease hippocampus

21 January 2018

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The excitotoxin quinolinic acid induces tau phosphorylation in human neurons

21 January 2018

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Involvement of quinolinic acid in AIDS dementia complex

21 January 2018

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The kynurenine pathway and quinolinic acid: pivotal roles in HIV associated neurocognitive disorders.

21 January 2018

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The kynurenine pathway and inflammation in amyotrophic lateral sclerosis

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Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis

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Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors

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Implications for the kynurenine pathway and quinolinic acid in amyotrophic lateral sclerosis.

21 January 2018

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Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease

21 January 2018

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Tryptophan metabolism and oxidative stress in patients with Huntington's disease

21 January 2018

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The quinolinic acid hypothesis in Huntington's chorea

21 January 2018

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Kynurenine pathway measurements in Huntington's disease striatum: evidence for reduced formation of kynurenic acid

21 January 2018

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Kynurenine metabolism in multiple sclerosis.

21 January 2018

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Kynurenines: from the perspective of major psychiatric disorders

21 January 2018

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Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types

21 January 2018

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Quinolinic acid production by macrophages stimulated with IFN-gamma, TNF-alpha, and IFN-alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat.

21 January 2018

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Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

21 January 2018

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Expression of the kynurenine enzymes in macrophages and microglial cells: regulation by immune modulators

21 January 2018

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Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia

21 January 2018

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Characterization of the kynurenine pathway in human neurons

21 January 2018

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Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway.

21 January 2018

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Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2.

21 January 2018

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Enzyme activities of tryptophan metabolism along the kynurenine pathway in various species of animals

21 January 2018

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Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO).

21 January 2018

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Species differences in L-tryptophan-kynurenine pathway metabolism: quantification of anthranilic acid and its related enzymes

21 January 2018

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Human microglia convert l-tryptophan into the neurotoxin quinolinic acid

21 January 2018

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Expression of the kynurenine pathway enzymes in human microglia and macrophages

21 January 2018

1 reference

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Tryptophan metabolism in rabbits

21 January 2018

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Tryptophan metabolism along the kynurenine pathway in rats

21 January 2018

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Quinolinate immunoreactivity in experimental rat brain tumors is present in macrophages but not in astrocytes

21 January 2018

1 reference

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Quinolinic acid neurotoxicity in the nucleus basalis antagonized by kynurenic acid

21 January 2018

1 reference

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Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons

21 January 2018

1 reference

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Kynurenine pathway metabolism in human blood-brain-barrier cells: implications for immune tolerance and neurotoxicity.

21 January 2018

1 reference

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Quinolinic acid phosphoribosyltransferase: preferential glial localization in the rat brain visualized by immunocytochemistry

21 January 2018

1 reference

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Immunohistochemical localization of quinolinic acid phosphoribosyltransferase in the human neostriatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Localization of quinolinic acid metabolizing enzymes in the rat brain. Immunohistochemical studies using antibodies to 3-hydroxyanthranilic acid oxygenase and quinolinic acid phosphoribosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Immunohistochemical identification of quinolinic acid phosphoribosyltransferase in glial cultures from rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Purification of quinolinic acid phosphoribosyltransferase from rat liver and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Differential vulnerability of central neurons of the rat to quinolinic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

NMDA receptors and ligands in the vertebrate CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Subtypes of NMDA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

The role of group I and group II metabotropic glutamate receptors in modulation of striatal NMDA and quinolinic acid toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

N-methyl-D-aspartate receptors mediating hippocampal noradrenaline and striatal dopamine release display differential sensitivity to quinolinic acid, the HIV-1 envelope protein gp120, external pH and protein kinase C inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

The pharmacological manipulation of glutamate receptors and neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Characterization of striatal cultures with the effect of QUIN and NMDA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Quinolinic acid is a potent lipid peroxidant in rat brain homogenates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Oxidative stress as a mechanism for quinolinic acid-induced hippocampal damage: protection by melatonin and deprenyl

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Quinolinic acid induces oxidative stress in rat brain synaptosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

In vivo hydroxyl radical formation after quinolinic acid infusion into rat corpus striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Enhanced neuronal damage by co-administration of quinolinic acid and free radicals, and protection by adenosine A2A receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Quinolinic acid-iron(ii) complexes: slow autoxidation, but enhanced hydroxyl radical production in the Fenton reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Quinolinate potentiates the neurotoxicity of excitatory amino acids in hypoxic neuronal tissue in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Changes in blood-brain barrier permeability following neurotoxic lesions of rat brain can be visualised with trypan blue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Bridging the gap between the immune and glutamate hypotheses of schizophrenia and major depression: Potential role of glial NMDA receptor modulators and impaired blood-brain barrier integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Quinolinic acid enhances permeability of rat brain microvessels to plasma albumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Acute intrastriatal administration of quinolinic acid provokes hyperphosphorylation of cytoskeletal intermediate filament proteins in astrocytes and neurons of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Characterisation of the expression of NMDA receptors in human astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

The involvement of astrocytes and kynurenine pathway in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

Quinolinic acid selectively induces apoptosis of human astrocytes: potential role in AIDS dementia complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X

The effect of quinolinate on rat brain lipid peroxidation is dependent on iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08485.X