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Autophagy modulation as a potential therapeutic target for diverse diseases
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PubMed
title
Autophagy modulation as a potential therapeutic target for diverse diseases
(English)
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PubMed
main subject
autophagy
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author
Patrice Codogno
series ordinal
2
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Beth Levine
series ordinal
3
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author name string
David C. Rubinsztein
series ordinal
1
1 reference
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Crossref
language of work or name
English
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stated in
PubMed
publication date
September 2012
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stated in
PubMed
published in
Nature Reviews Drug Discovery
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PubMed
volume
11
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stated in
PubMed
issue
9
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stated in
PubMed
page(s)
709-30
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PubMed
cites work
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
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Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks
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Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient muscles
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21 March 2017
Image-based genome-wide siRNA screen identifies selective autophagy factors
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21 March 2017
Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13
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21 March 2017
Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy
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21 March 2017
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth
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PubMed Central
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21 March 2017
Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
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21 March 2017
Autophagy in immunity and inflammation
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PubMed Central
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21 March 2017
Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex
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PubMed Central
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21 March 2017
ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death
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PubMed Central
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21 March 2017
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
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PubMed Central
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21 March 2017
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
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PubMed Central
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21 March 2017
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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21 March 2017
Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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21 March 2017
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
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PubMed Central
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21 March 2017
Autophagy suppresses tumorigenesis through elimination of p62
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PubMed Central
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21 March 2017
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
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PubMed Central
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21 March 2017
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
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PubMed Central
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21 March 2017
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
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PubMed Central
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21 March 2017
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2
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PubMed Central
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21 March 2017
Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation
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PubMed Central
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21 March 2017
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
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PubMed Central
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21 March 2017
Inhibition of macroautophagy triggers apoptosis
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21 March 2017
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
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PubMed Central
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21 March 2017
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
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PubMed Central
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21 March 2017
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
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PubMed Central
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21 March 2017
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
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21 March 2017
Structural basis of Atg8 activation by a homodimeric E1, Atg7
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21 March 2017
Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway
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PubMed Central
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21 March 2017
Mechanisms of mitophagy
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PubMed Central
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21 March 2017
Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34
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PubMed Central
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21 March 2017
Autophagy, Immunity, and Microbial Adaptations
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PubMed Central
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21 March 2017
Structural basis of target recognition by Atg8/LC3 during selective autophagy
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21 March 2017
Autophagy in the Pathogenesis of Disease
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PubMed Central
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21 March 2017
Unconventional secretion of Acb1 is mediated by autophagosomes.
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PubMed Central
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21 March 2017
Atg22 recycles amino acids to link the degradative and recycling functions of autophagy
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PubMed Central
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21 March 2017
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast
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PubMed Central
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21 March 2017
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
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21 March 2017
ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration
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21 March 2017
Induction of autophagy and inhibition of tumorigenesis by beclin 1
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21 March 2017
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
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21 March 2017
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
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PubMed Central
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21 March 2017
Loss of autophagy in the central nervous system causes neurodegeneration in mice
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PubMed Central
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21 March 2017
Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
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21 March 2017
Prevention of breast cancer in postmenopausal women: approaches to estimating and reducing risk
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21 March 2017
A block of autophagy in lysosomal storage disorders
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PubMed Central
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21 March 2017
Differential interactions between Beclin 1 and Bcl-2 family members
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PubMed Central
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21 March 2017
Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome
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21 March 2017
The roles of intracellular protein-degradation pathways in neurodegeneration
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21 March 2017
Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1
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21 March 2017
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
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21 March 2017
Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy
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21 March 2017
EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells
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PubMed Central
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21 March 2017
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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21 March 2017
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations
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PubMed Central
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21 March 2017
Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission
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PubMed Central
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21 March 2017
SNARE proteins are required for macroautophagy
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PubMed Central
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21 March 2017
3D tomography reveals connections between the phagophore and endoplasmic reticulum
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PubMed Central
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21 March 2017
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice
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PubMed Central
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21 March 2017
Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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21 March 2017
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
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7 April 2017
The role of Atg proteins in autophagosome formation
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7 April 2017
Autophagy regulates lipid metabolism
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7 April 2017
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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7 April 2017
The role of autophagy during the early neonatal starvation period
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7 April 2017
Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice
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7 April 2017
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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7 April 2017
Autophagy and aging
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7 April 2017
TFEB links autophagy to lysosomal biogenesis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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7 April 2017
Pancreatic cancers require autophagy for tumor growth
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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7 April 2017
Autophagy and metabolism
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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7 April 2017
Autophagy in mammalian development and differentiation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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7 April 2017
Eaten alive: a history of macroautophagy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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7 April 2017
Plasma membrane contributes to the formation of pre-autophagosomal structures
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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7 April 2017
Mitochondria supply membranes for autophagosome biogenesis during starvation
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PubMed Central
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7 April 2017
Induction of autophagy by spermidine promotes longevity
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PubMed Central
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7 April 2017
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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7 April 2017
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
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7 April 2017
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
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PubMed Central
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7 April 2017
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
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PubMed Central
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7 April 2017
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
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PubMed Central
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7 April 2017
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
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PubMed Central
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7 April 2017
FoxO3 controls autophagy in skeletal muscle in vivo
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PubMed Central
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7 April 2017
Role of autophagy in cancer
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7 April 2017
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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7 April 2017
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
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7 April 2017
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
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7 April 2017
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
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PubMed Central
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7 April 2017
Role for Rab7 in maturation of late autophagic vacuoles
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10 May 2017
Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma
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28 September 2017
Chikungunya virus-induced autophagy delays caspase-dependent cell death
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28 September 2017
Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity
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28 September 2017
PINK1- and Parkin-mediated mitophagy at a glance
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28 September 2017
α-Synuclein levels affect autophagosome numbers in vivo and modulate Huntington disease pathology
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PubMed Central
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28 September 2017
Inhibition of autophagy ameliorates acute lung injury caused by avian influenza A H5N1 infection.
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28 September 2017
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle
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28 September 2017
Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy
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28 September 2017
Ras-related tumorigenesis is suppressed by BNIP3-mediated autophagy through inhibition of cell proliferation
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28 September 2017
The human cytomegalovirus protein TRS1 inhibits autophagy via its interaction with Beclin 1
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28 September 2017
Targeting autophagy addiction in cancer
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28 September 2017
Vitamin D and cancer: a review of molecular mechanisms
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28 September 2017
Canonical and non-canonical autophagy: variations on a common theme of self-eating?
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28 September 2017
Autophagy and cancer
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28 September 2017
Autophagy in brain tumors: a new target for therapeutic intervention
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28 September 2017
Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion
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28 September 2017
Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors.
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28 September 2017
Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases.
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28 September 2017
Autophagy proteins regulate the secretory component of osteoclastic bone resorption
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28 September 2017
Cell death by autophagy: facts and apparent artefacts
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28 September 2017
Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
p62 is a key regulator of nutrient sensing in the mTORC1 pathway.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Autophagy required for hepatitis B virus replication in transgenic mice
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
SMURF1 amplification promotes invasiveness in pancreatic cancer
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
The role of autophagy in cancer: therapeutic implications
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Combining an EGFR directed tyrosine kinase inhibitor with autophagy-inducing drugs: a beneficial strategy to combat non-small cell lung cancer
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathway
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Autophagosome precursor maturation requires homotypic fusion
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200.
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28 September 2017
Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent
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28 September 2017
Involvement of mitophagy in oncogenic K-Ras-induced transformation: overcoming a cellular energy deficit from glucose deficiency
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28 September 2017
Complex inhibitory effects of nitric oxide on autophagy
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28 September 2017
Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis
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28 September 2017
Autophagy as a target for anticancer therapy
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28 September 2017
Relieving autophagy and 4EBP1 from rapamycin resistance
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28 September 2017
Biogenesis and cargo selectivity of autophagosomes
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28 September 2017
Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation
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28 September 2017
Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment
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28 September 2017
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells
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28 September 2017
Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis.
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28 September 2017
BH3 mimetics activate multiple pro-autophagic pathways
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28 September 2017
Hormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection
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28 September 2017
Preventive therapy for breast cancer: a consensus statement
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28 September 2017
Genome profiling of pancreatic adenocarcinoma
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28 September 2017
Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival
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28 September 2017
Principles and current strategies for targeting autophagy for cancer treatment
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28 September 2017
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
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28 September 2017
Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation
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28 September 2017
The Parkinson disease protein α-synuclein inhibits autophagy
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28 September 2017
Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
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28 September 2017
How ubiquitination and autophagy participate in the regulation of the cell response to bacterial infection
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28 September 2017
Dengue virus-induced autophagy regulates lipid metabolism
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28 September 2017
Regulation of mammalian autophagy in physiology and pathophysiology.
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28 September 2017
Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis.
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28 September 2017
Membrane Delivery to the Yeast Autophagosome from the Golgi–Endosomal System
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28 September 2017
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis
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28 September 2017
Oncosuppressive functions of autophagy
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28 September 2017
PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.
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28 September 2017
Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.
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28 September 2017
The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex
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28 September 2017
mTOR Mediated Anti-Cancer Drug Discovery
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28 September 2017
The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma.
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28 September 2017
A reporter cell system to monitor autophagy based on p62/SQSTM1.
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28 September 2017
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.
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28 September 2017
Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.
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28 September 2017
Starvation-induced hyperacetylation of tubulin is required for the stimulation of autophagy by nutrient deprivation
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28 September 2017
Autophagy and innate immunity: triggering, targeting and tuning
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28 September 2017
Genome-wide analysis of the host intracellular network that regulates survival of Mycobacterium tuberculosis.
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28 September 2017
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
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28 September 2017
In vivo requirement for Atg5 in antigen presentation by dendritic cells
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28 September 2017
Autophagy protects against Sindbis virus infection of the central nervous system
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28 September 2017
Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy
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28 September 2017
Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation.
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28 September 2017
Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases.
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28 September 2017
Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.
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28 September 2017
The Beclin 1 interactome
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28 September 2017
Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes
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PubMed Central
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28 September 2017
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
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28 September 2017
Chronic Mycobacterium abscessus infection and lung function decline in cystic fibrosis
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28 September 2017
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies
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28 September 2017
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
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28 September 2017
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases
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PubMed Central
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28 September 2017
Autophagy regulates adipose mass and differentiation in mice
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28 September 2017
Multicenter study of prevalence of nontuberculous mycobacteria in patients with cystic fibrosis in france
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28 September 2017
Viral Bcl-2-mediated evasion of autophagy aids chronic infection of gammaherpesvirus 68
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28 September 2017
Interaction of ICP34.5 with Beclin 1 modulates herpes simplex virus type 1 pathogenesis through control of CD4+ T-cell responses
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Autophagy genes in immunity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Selective types of autophagy in yeast.
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28 September 2017
Monitoring autophagy in lysosomal storage disorders
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Lifestyle factors and colorectal cancer risk (2): a systematic review and meta-analysis of associations with leisure-time physical activity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Beclin-1 expression is a predictor of clinical outcome in patients with esophageal squamous cell carcinoma and correlated to hypoxia-inducible factor (HIF)-1alpha expression
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
ARF induces autophagy by virtue of interaction with Bcl-xl.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Efficient cross-presentation depends on autophagy in tumor cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Vitamin D3 induces autophagy of human myeloid leukemia cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
A dual role of p53 in the control of autophagy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Spinocerebellar ataxias caused by polyglutamine expansions: a review of therapeutic strategies
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Pharmacologic characterization of a potent inhibitor of class I phosphatidylinositide 3-kinases.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Autophagy suppresses tumor progression by limiting chromosomal instability
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Lithium induces autophagy by inhibiting inositol monophosphatase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Dynein mutations impair autophagic clearance of aggregate-prone proteins
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Resveratrol-induced autophagocytosis in ovarian cancer cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Defective autophagy leads to cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Deletion of the SNARE vti1b in mice results in the loss of a single SNARE partner, syntaxin 8.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Physical activity and cancer prevention: etiologic evidence and biological mechanisms
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 September 2017
Pancreatic acinar cell-specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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31 May 2018
Autophagy-deficient mice develop multiple liver tumors
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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31 May 2018
Calcipotriol induces autophagy in HeLa cells and keratinocytes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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31 May 2018
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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31 May 2018
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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31 May 2018
Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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31 May 2018
Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Autophagy--alias self-eating--appetite and ageing
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Degradation of paternal mitochondria by fertilization-triggered autophagy in C. elegans embryos
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Clinicopathologic correlation of beclin-1 expression in pancreatic ductal adenocarcinoma.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Beclin 1 or not Beclin 1...
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
The prognostic role of Beclin 1 protein expression in high-grade gliomas.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
In search of an "autophagomometer".
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Mutant p53 protein localized in the cytoplasm inhibits autophagy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Autophagy is essential for preimplantation development of mouse embryos
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
ESCRTs and Fab1 regulate distinct steps of autophagy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3518431
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28 November 2018
Rapamycin pre-treatment protects against apoptosis
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28 November 2018
Rapamycin alleviates toxicity of different aggregate-prone proteins
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28 November 2018
Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases
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28 November 2018
Rab7 is required for the normal progression of the autophagic pathway in mammalian cells
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28 November 2018
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28 November 2018
α-Synuclein Is Degraded by Both Autophagy and the Proteasome
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28 November 2018
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28 November 2018
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease
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28 November 2018
Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
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28 November 2018
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy
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Autophagy: a potential link between obesity and insulin resistance
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Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice
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Beclin 1 expression predicts favorable clinical outcome in patients with diffuse large B-cell lymphoma treated with R-CHOP
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31 March 2020
BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)
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Effects of vinblastine, leucine, and histidine, and 3-methyladenine on autophagy in Ehrlich ascites cells
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Identifiers
DOI
10.1038/NRD3802
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
571701
Dimensions Publication ID
1045716500
0 references
OpenCitations bibliographic resource ID
571701
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
571701
PMC publication ID
3518431
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
571701
PubMed publication ID
22935804
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
571701
ResearchGate publication ID
230768583
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