(Q27106979)

Isofebrifugine (English)

5 October 2016

chemical formula

C₁₆H₁₉N₃O₃

1 reference

Isofebrifugine (English)

5 October 2016

canonical SMILES

C1CC2C(CC(O2)(CN3C=NC4=CC=CC=C4C3=O)O)NC1

1 reference

Isofebrifugine (English)

5 October 2016

isomeric SMILES

C1C[C@H]2[C@H](CC(O2)(CN3C=NC4=CC=CC=C4C3=O)O)NC1

1 reference

Isofebrifugine (English)

5 October 2016

found in taxon

Hydrangea macrophylla

2 references

Seasonal variation in the content of a febrifugine and isofebrifugine alkaloid mixture in aerial parts of Hydrangea macrophylla var. Otaksa, with special reference to its antimalarial activity

Different responses of three rodent Plasmodia species, Plasmodium yoelii 17XL, P. berghei NK65 and P. chabaudi AS on treatment with febrifugine and isofebrifugine mixture from Hydrangea macrophylla var. Otaksa leaf in ICR mice

Hydrangea febrifuga

2 references

New type of febrifugine analogues, bearing a quinolizidine moiety, show potent antimalarial activity against Plasmodium malaria parasite

Enhancement of NO production in activated macrophages in vivo by an antimalarial crude drug, Dichroa febrifuga

Identifiers

InChI

InChI=1S/C16H19N3O3/c20-15-11-4-1-2-5-12(11)18-10-19(15)9-16(21)8-13-14(22-16)6-3-7-17-13/h1-2,4-5,10,13-14,17,21H,3,6-9H2/t13-,14-,16?/m0/s1

1 reference

Isofebrifugine (English)

YLYLCQRQSRDSQR-ADTLFGHVSA-N

5 October 2016

InChIKey

2 references

Isofebrifugine (English)

5 October 2016

ChEBI release 2020-09-01

1 reference

Isofebrifugine (English)

5 October 2016

1 reference

3-{[(3aS,7aS)-2-Hydroxyoctahydrofuro[3,2-b]pyridin-2-yl]methyl}-4(3H)-quinazolinone (English)

5 October 2016

1 reference

3-{[(3aS,7aS)-2-Hydroxyoctahydrofuro[3,2-b]pyridin-2-yl]methyl}-4(3H)-quinazolinone (English)

5 October 2016

1 reference

Isofebrifugine (English)

5 October 2016

ChEBI ID

6008

mapping relation type

1 reference

Isofebrifugine (English)

5 October 2016

1 reference

DSSTOX compound identifier

ISOFEBRIFUGINE (English)

5 October 2016

1 reference

0 references

0 references

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1 reference

Isofebrifugine (English)

5 October 2016

1 reference

Isofebrifugine (English)