(Q27490476)

English

Crystal Structure of a Novel Conformational State of the Flavivirus NS3 Protein: Implications for Polyprotein Processing and Viral Replication

scientific article

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793813%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Crystal structure of a novel conformational state of the flavivirus NS3 protein: implications for polyprotein processing and viral replication (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793813%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

viral genome replication

1 reference

based on heuristic

inferred from abstract

crystal structure

0 references

protein structure

0 references

1 reference

structural biology

1 reference

dengue virus protein NS3

1 reference

based on heuristic

inferred from abstract

5

1 reference

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8 February 2020

Eloise Mastrangelo

2

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8 February 2020

Thomas S. Walter

3

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8 February 2020

6

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8 February 2020

David Ian Stuart

7

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8 February 2020

Erika J Mancini

9

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8 February 2020

Jonathan Grimes

8

object named as

Jonathan M Grimes

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8 February 2020

author name string

René Assenberg

1

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8 February 2020

Anil Verma

4

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8 February 2020

publication date

30 September 2009

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8 February 2020

Journal of Virology

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8 February 2020

83

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8 February 2020

12895-12906

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8 February 2020

24

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8 February 2020

describes a project that uses

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11 June 2022

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Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation

1 reference

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20 March 2017

Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein

1 reference

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Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus

1 reference

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1 reference

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Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis

1 reference

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Yellow Fever Virus NS3 Plays an Essential Role in Virus Assembly Independent of Its Known Enzymatic Functions

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Crystal Structure of the NS3 Protease-Helicase from Dengue Virus

1 reference

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Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein

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20 March 2017

Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues

1 reference

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20 March 2017

Structural evidence for regulation and specificity of flaviviral proteases and evolution of theFlaviviridaefold

1 reference

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20 March 2017

Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase

1 reference

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20 March 2017

Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 A

1 reference

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20 March 2017

Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing

1 reference

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20 March 2017

An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

1 reference

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20 March 2017

Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes

1 reference

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20 March 2017

Mutagenesis of the Dengue virus type 2 NS3 protein within and outside helicase motifs: effects on enzyme activity and virus replication

1 reference

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Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

1 reference

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20 March 2017

The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786852

20 March 2017

trans-Complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells

1 reference

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20 March 2017

RNA-protein interactions: involvement of NS3, NS5, and 3' noncoding regions of Japanese encephalitis virus genomic RNA

1 reference

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Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes

1 reference

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20 March 2017

Flavivirus genome organization, expression, and replication

1 reference

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20 March 2017

Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins

1 reference

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20 March 2017

Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 A

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20 March 2017

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The CCP4 suite: programs for protein crystallography

1 reference

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PHENIX: building new software for automated crystallographic structure determination

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

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Main-chain bond lengths and bond angles in protein structures

1 reference

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1 reference

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1 reference

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Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.

1 reference

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Modulation of the nucleoside triphosphatase/RNA helicase and 5'-RNA triphosphatase activities of Dengue virus type 2 nonstructural protein 3 (NS3) by interaction with NS5, the RNA-dependent RNA polymerase.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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27 November 2018

Identifiers

10.1128/JVI.00942-09

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793813%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793813%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

Europe PubMed Central

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8 February 2020

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