(Q27549729)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08539

Fungal G-protein, alpha subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08539

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08539

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

signal transducer activity

GTPase activity

Mutations in the guanine nucleotide-binding domains of a yeast G alpha protein confer a constitutive or uninducible state to the pheromone response pathway

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

5 June 2018

5 June 2018

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

1 reference

9 May 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

1 reference

9 May 2019

guanyl nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

1 reference

9 May 2019

protein binding

9 references

9 May 2019

Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

Interactions among the subunits of the G protein involved in Saccharomyces cerevisiae mating.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

The Leu-132 of the Ste4(Gbeta) subunit is essential for proper coupling of the G protein with the Ste2 alpha factor receptor during the mating pheromone response in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

Genetic identification of residues involved in association of alpha and beta G-protein subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

G-protein beta-subunit binding

1 reference

9 May 2019

Interactions among the subunits of the G protein involved in Saccharomyces cerevisiae mating.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

GTPase activity

Mutations in the guanine nucleotide-binding domains of a yeast G alpha protein confer a constitutive or uninducible state to the pheromone response pathway

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

9 May 2019

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

heterotrimeric G-protein complex

cell component

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

5 June 2018

Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

5 June 2018

5 June 2018

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

1 reference

9 May 2019

endosome membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

1 reference

9 May 2019

heterotrimeric G-protein complex

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

9 May 2019

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

cytosol

HDA

1 reference

9 May 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion

HDA

biological process

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

1 reference

9 May 2019

response to pheromone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

1 reference

9 May 2019

nuclear migration involved in conjugation with cellular fusion

1 reference

9 May 2019

The mating-specific Galpha interacts with a kinesin-14 and regulates pheromone-induced nuclear migration in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

regulation of MAPK export from nucleus

1 reference

9 May 2019

Effect of the pheromone-responsive G(alpha) and phosphatase proteins of Saccharomyces cerevisiae on the subcellular localization of the Fus3 mitogen-activated protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

inositol lipid-mediated signaling

1 reference

9 May 2019

Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

karyogamy involved in conjugation with cellular fusion

1 reference

9 May 2019

The mating-specific Galpha interacts with a kinesin-14 and regulates pheromone-induced nuclear migration in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

pheromone-dependent signal transduction involved in conjugation with cellular fusion

IGI

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference