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Isy1p YJR050W
fungal protein found in Saccharomyces cerevisiae S288c
Isy1p
ISY1
YJR050W
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P21374
subclass of
protein
1 reference
stated in
NCBI Gene
retrieved
10 December 2016
Entrez Gene ID
853509
part of
Pre-mRNA-splicing factor Isy1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P21374
Pre-mRNA-splicing factor Isy1 superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P21374
Helix hairpin bin domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P21374
found in taxon
Saccharomyces cerevisiae S288c
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P21374
encoded by
ISY1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P21374
molecular function
second spliceosomal transesterification activity
determination method
IC
1 reference
retrieved
9 May 2019
stated in
The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IC
first spliceosomal transesterification activity
determination method
IGI
1 reference
retrieved
16 July 2018
stated in
The Isy1p component of the NineTeen complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21374&geneProductId=UniProtKB:P21374
determination method
IGI
protein binding
determination method
IPI
6 references
retrieved
9 May 2019
stated in
High-quality binary protein interaction map of the yeast interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IPI
retrieved
9 May 2019
stated in
Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IPI
retrieved
9 May 2019
stated in
Functional and physical interactions between components of the Prp19p-associated complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IPI
retrieved
9 May 2019
stated in
Proteome survey reveals modularity of the yeast cell machinery
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IPI
retrieved
9 May 2019
stated in
Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IPI
retrieved
9 May 2019
stated in
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IPI
first spliceosomal transesterification activity
determination method
IBA
IGI
2 references
retrieved
9 May 2019
stated in
The Isy1p component of the NineTeen complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IGI
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IBA
cell component
post-mRNA release spliceosomal complex
determination method
IDA
1 reference
retrieved
16 July 2018
stated in
The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21374&geneProductId=UniProtKB:P21374
determination method
IDA
spliceosomal complex
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IEA
cytoplasm
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IEA
nucleus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IEA
U2-type catalytic step 2 spliceosome
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IDA
post-spliceosomal complex
determination method
IDA
1 reference
retrieved
16 July 2018
stated in
The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21374&geneProductId=UniProtKB:P21374
determination method
IDA
U2-type catalytic step 1 spliceosome
determination method
IDA
2 references
retrieved
9 May 2019
stated in
Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IDA
retrieved
9 May 2019
stated in
The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IDA
Prp19 complex
determination method
IDA
1 reference
retrieved
16 July 2018
stated in
Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21374&geneProductId=UniProtKB:P21374
determination method
IDA
Prp19 complex
determination method
IBA
IDA
2 references
retrieved
9 May 2019
stated in
Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IBA
catalytic step 2 spliceosome
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IBA
post-mRNA release spliceosomal complex
determination method
IBA
IDA
2 references
retrieved
9 May 2019
stated in
The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IBA
post-spliceosomal complex
determination method
IBA
IDA
2 references
retrieved
9 May 2019
stated in
The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IBA
biological process
mRNA processing
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IEA
RNA splicing
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IEA
mRNA 3'-splice site recognition
determination method
IMP
1 reference
retrieved
16 July 2018
stated in
The Isy1p component of the NineTeen complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21374&geneProductId=UniProtKB:P21374
determination method
IMP
generation of catalytic spliceosome for second transesterification step
determination method
IEA
IMP
2 references
retrieved
16 July 2018
stated in
The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21374&geneProductId=UniProtKB:P21374
determination method
IMP
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21374&geneProductId=UniProtKB:P21374
determination method
IEA
generation of catalytic spliceosome for second transesterification step
determination method
IBA
IEA
IMP
3 references
retrieved
9 May 2019
stated in
The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IMP
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IBA
mRNA 3'-splice site recognition
determination method
IBA
IMP
2 references
retrieved
9 May 2019
stated in
The Isy1p component of the NineTeen complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IMP
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21374
determination method
IBA
Identifiers
RefSeq protein ID
NP_012584
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
853509
UniProt protein ID
P21374
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P21374
Ensembl protein ID
YJR050W
1 reference
stated in
ensembl Release 106
Ensembl protein ID
YJR050W
Saccharomyces Genome Database ID
S000003811
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
853509
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