(Q27629132)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11136978%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma (English)

1 reference

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3 November 2019

0 references

3

1 reference

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3 November 2019

Roger L. Williams

10

1 reference

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3 November 2019

author name string

M E Pacold

1

1 reference

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3 November 2019

S Suire

2

1 reference

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3 November 2019

S Lara-Gonzalez

4

1 reference

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3 November 2019

C T Davis

5

1 reference

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3 November 2019

E H Walker

6

1 reference

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3 November 2019

P T Hawkins

7

1 reference

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3 November 2019

L Stephens

8

1 reference

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3 November 2019

J F Eccleston

9

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3 November 2019

language of work or name

English

0 references

publication date

1 December 2000

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3 November 2019

1 reference

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3 November 2019

volume

103

1 reference

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3 November 2019

page(s)

931-943

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3 November 2019

issue

6

1 reference

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Interfacial catalysis by phosphoinositide 3'-hydroxykinase.

3 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Plasma-membrane location of phosphatidylinositol hydrolysis in rabbit neutrophils stimulated with formylmethionyl-leucylphenylalanine.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

The structural basis of the activation of Ras by Sos

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Priming of human neutrophil superoxide generation by tumour necrosis factor-alpha is signalled by enhanced phosphatidylinositol 3,4,5-trisphosphate but not inositol 1,4,5-trisphosphate accumulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

A redox-triggered ras-effector interaction. Recruitment of phosphatidylinositol 3'-kinase to Ras by redox stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Using structure to define the function of phosphoinositide 3-kinase family members.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Accurate bond and angle parameters for X-ray protein structure refinement

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Evidence for a Ras/Ral signaling cascade.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

PI3K: downstream AKTion blocks apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

PI-3-kinase is an essential anti-apoptotic effector in the proliferative response of primary human epithelial cells to mutant RAS

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

New ribose-modified fluorescent analogs of adenine and guanine nucleotides available as substrates for various enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Structural basis for the interaction of Ras with RalGDS

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Fluorescent nucleotide analogs: synthesis and applications.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Distinct Mechanisms of α5β1Integrin Activation by Ha-Ras and R-Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Experimental assessment of differences between related protein crystal structures.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Function and regulation of ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Roles of non-catalytic subunits in gbetagamma-induced activation of class I phosphoinositide 3-kinase isoforms beta and gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Raster3D: photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Mechanism of GTP hydrolysis by p21N-ras catalyzed by GAP: studies with a fluorescent GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Phosphatidylinositol 3' kinase: one of the effectors of Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Interaction of Ras with phosphoinositide 3-kinase gamma.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Farnesylation of Ras is important for the interaction with phosphoinositide 3-kinase gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Regulation of the rate and extent of phospholipase C beta 2 effector activation by the beta gamma subunits of heterotrimeric G proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Understanding Ras: 'it ain't over 'til it's over'.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

The conserved phosphoinositide 3-kinase pathway determines heart size in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Transient Kinetic Studies on the Interaction of Ras and the Ras-Binding Domain of c-Raf-1 Reveal Rapid Equilibration of the Complex†

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

P110delta, a novel phosphoinositide 3-kinase in leukocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Structural and biochemical analysis of Ras-effector signaling via RalGDS

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Structural insights into phosphoinositide 3-kinase catalysis and signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Multiple Ras functions can contribute to mammalian cell transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Ras-effector interactions, the problem of specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Lipids on the move: phosphoinositide 3-kinases in leukocyte function.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

Participation of ADP dissociation in the rate-determining step in cAMP-dependent protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900196-3

7 January 2021

10.1016/S0092-8674(00)00196-3

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

1626791

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11136978%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1626791

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

1626791