(Q27641951)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

Cyclopropyl-{4-[5-(3,4-Dichlorophenyl)-2-[(1-Methyl)-Piperidin]-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine

7 November 2019

main subject

1 reference

ChEBI release 2020-05-28

1

0 references

author name string

Sangita B Patel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

JeanMarie Lisnock

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Joseph W Becker

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Philip V LoGrasso

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Giovanna Scapin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

publication date

1 August 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

published in

Chemistry and Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

page(s)

705-712

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

7 November 2019

cites work

1 reference

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7 January 2021

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

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7 January 2021

Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

1 reference

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7 January 2021

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

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7 January 2021

Selective interaction of JNK protein kinase isoforms with transcription factors

1 reference

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7 January 2021

p493F12 kinase: a novel MAP kinase expressed in a subset of neurons in the human nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Developmental expression in the mouse nervous system of the p493F12 SAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Mammalian MAP kinase signalling cascades

1 reference

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7 January 2021

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

ATP site-directed competitive and irreversible inhibitors of protein kinases

1 reference

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7 January 2021

Chemical inhibitors of protein kinases

1 reference

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7 January 2021

Structural basis of inhibitor selectivity in MAP kinases

1 reference

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7 January 2021

Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors

1 reference

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7 January 2021

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Structure-based design of cyclin-dependent kinase inhibitors

1 reference

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7 January 2021

Structural biology in drug design: selective protein kinase inhibitors

1 reference

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7 January 2021

Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Crystal structure of JNK3: a kinase implicated in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Molecular basis for p38 protein kinase inhibitor specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Mechanism-based design of a protein kinase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Activation of JNK3 alpha 1 requires both MKK4 and MKK7: kinetic characterization of in vitro phosphorylated JNK3 alpha 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Electron-density map interpretation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Torsion angle dynamics: reduced variable conformational sampling enhances crystallographic structure refinement

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

AMoRe: an automated package for molecular replacement

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900159-5

7 January 2021

10.1016/S1074-5521(03)00159-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12954329%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference