(Q27645597)

3

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author name string

Galen E Flynn

1

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Kevin D Black

2

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William N Zagotta

Structural basis for modulation and agonist specificity of HCN pacemaker channels

5

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publication date

June 2007

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published in

Structure

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volume

15

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page(s)

671-82

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issue

6

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cites work

1 reference

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Structure and regulation of the cAMP-binding domains of Epac2

20 March 2017

1 reference

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A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase

20 March 2017

1 reference

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

20 March 2017

1 reference

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Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains

20 March 2017

1 reference

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Coot: model-building tools for molecular graphics

20 March 2017

1 reference

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The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

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MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes

20 March 2017

1 reference

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

20 March 2017

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

1 reference

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

20 March 2017

1 reference

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Electron-density map interpretation

20 March 2017

1 reference

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Recent developments in the PHENIX software for automated crystallographic structure determination

7 April 2017

1 reference

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Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel.

29 September 2017

1 reference

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29 September 2017

1 reference

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Inactivation in HCN channels results from reclosure of the activation gate: desensitization to voltage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Structure and function of glutamate receptor ion channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Hyperpolarization-activated cation currents: from molecules to physiological function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Cardiac HCN channels: structure, function, and modulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Molecular diversity of pacemaker ion channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Molecular identification of a hyperpolarization-activated channel in sea urchin sperm

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Queer current and pacemaker: the hyperpolarization-activated cation current in neurons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Predicted ligand interactions of 3'5'-cyclic nucleotide-gated channel binding sites: comparison of retina and olfactory binding site models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Mutagenesis of the cyclic AMP receptor protein of Escherichia coli: targeting positions 83, 127 and 128 of the cyclic nucleotide binding pocket

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Gating of single Shaker potassium channels in Drosophila muscle and in Xenopus oocytes injected with Shaker mRNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

The contribution of the 'pacemaker' current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Control of ligand specificity in cyclic nucleotide-gated channels from rod photoreceptors and olfactory epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Integrated allosteric model of voltage gating of HCN channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Cyclic nucleotide-gated channels: structural basis of ligand efficacy and allosteric modulation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

A simple electrostatic switch important in the activation of type I protein kinase A by cyclic AMP.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Localization of regions affecting an allosteric transition in cyclic nucleotide-activated channels.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Predicted structures of the cGMP binding domains of the cGMP-dependent protein kinase: a key alanine/threonine difference in evolutionary divergence of cAMP and cGMP binding sites

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219339

Muscarinic modulation of cardiac rate at low acetylcholine concentrations

27 November 2018

1 reference

12 December 2020

Molecular model of the cyclic GMP-binding domain of the cyclic GMP-gated ion channel

1 reference

12 December 2020

Interaction at End-Plate Receptors between Different Choline Derivatives

1 reference

12 December 2020

Crystal structure of a cyclic AMP-independent mutant of catabolite gene activator protein

1 reference

12 December 2020

Nonstationary noise analysis and application to patch clamp recordings

1 reference

12 December 2020

Thermodynamics of the interaction of barnase and barstar: changes in free energy versus changes in enthalpy on mutation

1 reference

12 December 2020

Molecular mechanism for ligand discrimination of cyclic nucleotide-gated channels

1 reference

12 December 2020

10.1016/J.STR.2007.04.008

Identifiers

DOI

1 reference

4707624

4707624

1 reference

1 reference

1 reference