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Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue

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Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue (English)

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H M Pereira

1

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V Berdini

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2

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A Cleasby

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3

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R C Garratt

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4

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language of work or name

English

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publication date

30 October 2007

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published in

FEBS Letters

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volume

581

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page(s)

5082-6

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issue

26

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cites work

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Consideration of molecular weight during compound selection in virtual target-based database screening.

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Fragment-based lead discovery using X-ray crystallography.

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Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues

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An approach to multi-copy search in molecular replacement

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Refinement of macromolecular structures by the maximum-likelihood method

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X-LIGAND: an application for the automated addition of flexible ligands into electron density.

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PROCHECK: a program to check the stereochemical quality of protein structures

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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A ‘Rule of Three’ for fragment-based lead discovery?

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Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with hypoxanthine at 2.15 A resolution

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Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase

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(Q27648745)

Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue

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