(Q27766894)

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Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir

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12 December 2019

Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir (English)

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12 December 2019

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12 December 2019

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M S Bennett

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12 December 2019

J N Champness

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12 December 2019

T Batuwangala

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12 December 2019

T Rutherford

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12 December 2019

W C Summers

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12 December 2019

H Sun

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12 December 2019

G Wright

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12 December 2019

M R Sanderson

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1 January 1999

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12 December 2019

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12 December 2019

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12 December 2019

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12 December 2019

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12 December 2019

Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Targeting of an inducible toxic phenotype in animal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Synthesis, properties, and pharmacokinetic studies of N2-phenylguanine derivatives as inhibitors of herpes simplex virus thymidine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

9-(4-Hydroxybutyl)-N2-phenylguanine (HBPG), a thymidine kinase inhibitor, suppresses herpes virus reactivation in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Effect of 9-(4-hydroxybutyl)-N2-phenylguanine (HBPG), a thymidine kinase inhibitor, on clinical recurrences of ocular herpetic keratitis in squirrel monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Prediction of the binding mode of N2-phenylguanine derivative inhibitors to herpes simplex virus type 1 thymidine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Crystal structures of the thymidine kinase from herpes simplex virus type-1 in complex with deoxythymidine and ganciclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

The three-dimensional structure of thymidine kinase from herpes simplex virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Purification and crystallization of thymidine kinase from herpes simplex virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Crystallographic R factor refinement by molecular dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

5-Substituted pyrimidines with a 1,5-anhydro-2, 3-dideoxy-D-arabino-hexitol moiety at N-1: synthesis, antiviral activity, conformational analysis, and interaction with viral thymidine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Role of Herpes simplex Virus Thymidine Kinase Expression in Viral Pathogenesis and Latency

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901619-6

21 January 2018

Identifiers

10.1016/S0014-5793(98)01619-6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9989588%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9989588%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

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