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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
scientific article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
19029981
retrieved
13 November 2016
title
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
(English)
1 reference
stated in
PubMed
PubMed ID
19029981
retrieved
13 November 2016
author
Ralph Weissleder
series ordinal
18
0 references
Kwok Kin Wong
series ordinal
21
object named as
Kwok-Kin Wong
0 references
Lewis C. Cantley
object named as
Lewis C Cantley
series ordinal
20
0 references
Umar Mahmood
series ordinal
19
object named as
Umar Mahmood
0 references
Rabi Upadhyay
series ordinal
6
object named as
Rabi Upadhyay
0 references
author name string
Jeffrey A Engelman
series ordinal
1
0 references
Liang Chen
series ordinal
2
0 references
Xiaohong Tan
series ordinal
3
0 references
Katherine Crosby
series ordinal
4
0 references
Alexander R Guimaraes
series ordinal
5
0 references
Michel Maira
series ordinal
7
0 references
Kate McNamara
series ordinal
8
0 references
Samanthi A Perera
series ordinal
9
0 references
Youngchul Song
series ordinal
10
0 references
Lucian R Chirieac
series ordinal
11
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Ramneet Kaur
series ordinal
12
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Angela Lightbown
series ordinal
13
0 references
Jessica Simendinger
series ordinal
14
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Timothy Li
series ordinal
15
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Robert F Padera
series ordinal
16
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Carlos García-Echeverría
series ordinal
17
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language of work or name
English
0 references
publication date
December 2008
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published in
Nature Medicine
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volume
14
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page(s)
1351-6
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issue
12
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cites work
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KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.
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High frequency of mutations of the PIK3CA gene in human cancers
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Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit
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Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
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PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab
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The role of phosphoinositide 3-kinase pathway inhibitors in the treatment of lung cancer
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Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy
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Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor
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"Oncogenic shock": explaining oncogene addiction through differential signal attenuation
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The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells
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Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase
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Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice
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PIK3CA mutations and PTEN loss correlate with similar prognostic factors and are not mutually exclusive in breast cancer
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Conditional gene expression in the respiratory epithelium of the mouse.
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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.1890
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol 3-kinase mediates bronchioalveolar stem cell expansion in mouse models of oncogenic K-ras-induced lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNM.1890
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NM.1890
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
867342
Dimensions Publication ID
1000532983
0 references
OpenCitations bibliographic resource ID
867342
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
867342
PMCID
2683415
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
867342
PubMed ID
19029981
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
867342
ResearchGate publication ID
232787804
0 references
Springer Nature article ID
10.1038/nm.1890
0 references
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