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Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer
scientific article
Concomitant BRAF and PI3K/mTOR Blockade Is Required for Effective Treatment of BRAFV600E Colorectal Cancer
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scholarly article
1 reference
stated in
PubMed
PubMed ID
23549875
retrieved
13 November 2016
title
Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer
(English)
1 reference
stated in
PubMed
PubMed ID
23549875
retrieved
13 November 2016
main subject
colorectal cancer
1 reference
based on heuristic
inferred from title
colorectal carcinoma
1 reference
based on heuristic
inferred from title
author
Sabine Tejpar
series ordinal
12
object named as
Sabine Tejpar
0 references
Jatin Roper
object named as
Jatin Roper
series ordinal
3
1 reference
stated in
ORCID Public Data File 2021
Roderick Bronson
series ordinal
11
object named as
Roderick T Bronson
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author name string
Erin M Coffee
series ordinal
1
0 references
Anthony C Faber
series ordinal
2
0 references
Mark J Sinnamon
series ordinal
4
0 references
Gautam Goel
series ordinal
5
0 references
Lily Keung
series ordinal
6
0 references
Wei Vivian Wang
series ordinal
7
0 references
Loredana Vecchione
series ordinal
8
0 references
Veerle de Vriendt
series ordinal
9
0 references
Barbara J Weinstein
series ordinal
10
0 references
Ramnik J Xavier
series ordinal
13
0 references
Jeffrey A Engelman
series ordinal
14
0 references
Eric S Martin
series ordinal
15
0 references
Kenneth E Hung
series ordinal
16
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language of work or name
English
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publication date
15 May 2013
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published in
Clinical Cancer Research
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volume
19
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page(s)
2688-98
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issue
10
0 references
cites work
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Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K
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PubMed Central
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PubMed Central
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
Antitumor efficacy of the novel RAF inhibitor GDC-0879 is predicted by BRAFV600E mutational status and sustained extracellular signal-regulated kinase/mitogen-activated protein kinase pathway suppression.
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29 September 2017
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A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors
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29 September 2017
BRAF targeted therapy changes the treatment paradigm in melanoma
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2 June 2018
V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a
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2 June 2018
Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf
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2 June 2018
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27 November 2018
Suppression of BRAF(V599E) in human melanoma abrogates transformation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23549875
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Poor Survival Associated with theBRAFV600E Mutation in Microsatellite-Stable Colon Cancers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23549875
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Use of mononucleotide repeat markers for detection of microsatellite instability in mouse tumors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23549875
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Sessile serrated adenoma with early neoplastic progression: a clinicopathologic and molecular study
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23549875
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Serrated Colorectal Neoplasia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23549875
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/1078-0432.CCR-12-2556
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4748037
OpenCitations bibliographic resource ID
4748037
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4748037
PMCID
3815598
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4748037
PubMed ID
23549875
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4748037
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