(Q27852333)

English

Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial.

scientific article

In more languages

Statements

scholarly article

2 references

13 November 2016

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

phase III clinical trial

0 references

0 references

1 reference

based on heuristic

inferred from title

head and neck squamous cell carcinoma

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Sandrine Faivre

12

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

15

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Bruce Allen Bach

18

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Krzysztof Skladowski

9

object named as

Krzysztof Skladowski

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Jan B Vermorken

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Jan Stöhlmacher-Williams

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Irina Davidenko

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Eric Winquist

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Cristian Villanueva

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Paolo Foa

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Sylvie Rottey

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Makoto Tahara

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Vasant R Pai

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Cesar R Blajman

13

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Arlene A Forastiere

14

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Kelly S Oliner

16

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Zhiying Pan

17

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

SPECTRUM investigators

19

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

publication date

6 June 2013

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Lancet Oncology Commission

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

14

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

697-710

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck. A phase III study of the EORTC

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): an intergroup trial of the Eastern Cooperative Oncology Group

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The molecular biology of head and neck cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Platinum-based chemotherapy plus cetuximab in head and neck cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Exploring biomarkers in head and neck cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for a causal association between human papillomavirus and a subset of head and neck cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human papillomavirus and survival of patients with oropharyngeal cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Survival and human papillomavirus in oropharynx cancer in TAX 324: a subset analysis from an international phase III trial.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Burden of potentially human papillomavirus-associated cancers of the oropharynx and oral cavity in the US, 1998-2003.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic patterns in head and neck cancers that contain or lack transcriptionally active human papillomavirus.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

HPV integration begins in the tonsillar crypt and leads to the alteration of p16, EGFR and c-myc during tumor formation.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationship between epidermal growth factor receptor status, p16(INK4A), and outcome in head and neck squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationships between epidermal growth factor receptor expression and human papillomavirus status as markers of prognosis in oropharyngeal cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular and Cytogenetic Subgroups of Oropharyngeal Squamous Cell Carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Panitumumab in combination with cytotoxic chemotherapy for the treatment of metastatic colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Augmentation of radiation response by panitumumab in models of upper aerodigestive tract cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparing ELISA and surface plasmon resonance for assessing clinical immunogenicity of panitumumab

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Interval estimation for the difference between independent proportions: comparison of eleven methods

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Prognostic factors and long-term survivorship in patients with recurrent or metastatic carcinoma of the head and neck.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human Papillomavirus Types in Head and Neck Squamous Cell Carcinomas Worldwide: A Systematic Review

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Partial p16 staining in oropharyngeal squamous cell carcinoma: extent and pattern correlate with human papillomavirus RNA status.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Is p16 immunohistochemistry a more cost-effective method for identification of human papilloma virus-associated head and neck squamous cell carcinoma?

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Tissue distribution of human papillomavirus 16 DNA integration in patients with tonsillar carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5–8

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular classification identifies a subset of human papillomavirus--associated oropharyngeal cancers with favorable prognosis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Zalutumumab plus best supportive care versus best supportive care alone in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after failure of platinum-based chemotherapy: an open-label, randomised phase 3 trial

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1470-2045(13)70181-5

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27852333&oldid=1953657007"